词条 | Sulfur dioxygenase |
释义 |
| Name = Sulfur dioxygenase | EC_number = 1.13.11.18 | CAS_number = 37256-58-9 | IUBMB_EC_number = 1/13/11/18 | GO_code = | image = | width = | caption = }}Sulfur dioxygenase ({{EC number|1.13.11.18}}, sulfur oxygenase, sulfur:oxygen oxidoreductase) is an enzyme with systematic name S-sulfanylglutathione:oxygen oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction sulfur + O2 + H2O sulfite + 2 H+ (overall reaction) (1a) glutathione + sulfur S-sulfanylglutathione (spontaneous reaction) (1b) S-sulfanylglutathione + O2 + H2O glutathione + sulfite + 2 H+ This enzyme contains iron. In humans, sulfur dioxygenase is needed to detoxify sulfide.[3] References1. ^{{cite journal | vauthors = Suzuki I, Silver M | title = The initial product and properties of the sulfur-oxidizing enzyme of thiobacilli | journal = Biochimica et Biophysica Acta | volume = 122 | issue = 1 | pages = 22–33 | date = July 1966 | pmid = 5968172 | doi = 10.1016/0926-6593(66)90088-9 }} 2. ^{{cite journal | vauthors = Rohwerder T, Sand W | title = The sulfane sulfur of persulfides is the actual substrate of the sulfur-oxidizing enzymes from Acidithiobacillus and Acidiphilium spp | journal = Microbiology | volume = 149 | issue = Pt 7 | pages = 1699–710 | date = July 2003 | pmid = 12855721 | doi = 10.1099/mic.0.26212-0 }} 3. ^{{cite journal | vauthors = Viscomi C, Burlina AB, Dweikat I, Savoiardo M, Lamperti C, Hildebrandt T, Tiranti V, Zeviani M | title = Combined treatment with oral metronidazole and N-acetylcysteine is effective in ethylmalonic encephalopathy | journal = Nature Medicine | volume = 16 | issue = 8 | pages = 869–71 | date = August 2010 | pmid = 20657580 | doi = 10.1038/nm.2188 }} External links
1 : EC 1.13.11 |
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