| 词条 | Topaquinone |
| 释义 |
| ImageFile = Topaquinone structure.svg | ImageSize = 200px | ImageAlt = | IUPACName = (2S)-2-Amino-3-(4-hydroxy-3,6-dioxocyclohexa-1,4-dien-1-yl)propanoic acid | OtherNames = 6-Hydroxydopaquinone | Section1 = {{Chembox Identifiers | CASNo = 64192-68-3 | PubChem = 123871 | SMILES = | Section2 = {{Chembox Properties | C=9 | H=9 | N=1 | O=5 | MolarMass = | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}Topaquinone (TPQ) is a redox cofactor derived from the amino acid tyrosine. Its name derives from 2,4,5-trihydroxyphenylalanine-quinone. Its structure was first identified in 1990.[1] It is used by copper amine oxidases which contain a tyrosine residue near the active site. This residue catalyses its own transition, first to dopaquinone and then to topaquinone, in a Cu2+ dependent manner.[1] References1. ^1 {{Cite journal|title = Structure and biogenesis of topaquinone and related cofactors |journal = Journal of Biological Inorganic Chemistry |date = Feb 1999|issn = 0949-8257|pmid = 10499097|pages = 1–11|volume = 4|issue = 1|first = D. M.|last = Dooley}} 5 : Cofactors|Amino acid derivatives|1,4-Benzoquinones|Hydroxybenzoquinones|Propionic acids |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。