Trans-Sahara may refer to:

• Trans-Saharan trade route
• Trans-Sahara Highway, a transnational highway
• Operation Enduring Freedom – Trans Sahara

• Prostanthera cuneata
• Prostanthera eurybioides
• Prostanthera galbraithiae
• Prostanthera melissifolia
• Prostanthera nivea
• Prostanthera ovalifolia
• Prostanthera phylicifolia
• Prostap
• Prostap 3
• Prostaphin
• Prostaphlin
• Prostap SR
• Prostar Stadium
• ProstaScint
• Prostascint
• Prostasome
• Prostasomes
• ProStat
• Prostate adenocarcinoma
• Prostate apoptosis response-4
• Prostate brachytherapy
• Prostate cancer folate supplementation
• Prostate Cancer Foundation
• Prostates
• Prostate specific antigen