Of the 10 Missouri incumbents, 8 were re-elected.
| District | Incumbent | Party | First
elected | Result | Candidates |
|---|
| Missouri|1|X}} | Bill Clay | Democratic | 1968 | Incumbent re-elected. | √ Bill Clay (Democratic) 64.0%
Richard O. Funsch (Republican) 36.0% |
| Missouri|2|X}} | James W. Symington | Democratic | 1968 | Incumbent re-elected. | √ James W. Symington (Democratic) 63.5%
John W. 'Jack' Cooper Jr. (Republican) 36.5% |
| Missouri|3|X}} | Leonor Sullivan | Democratic | 1952 | Incumbent re-elected. | √ Leonor Sullivan (Democratic) 69.3%
Albert Holst (Republican) 30.4%
Charles H. Byford (Independent) 0.3% |
| Missouri|4|X}} | William J. Randall | Democratic | 1959 | Incumbent re-elected. | √ William J. Randall (Democratic) 57.4%
Raymond E. Barrows (Republican) 42.6% |
| Missouri|5|X}} | Richard Bolling | Democratic | 1948 | Incumbent re-elected. | √ Richard Bolling (Democratic) 62.8%
Vernon E. Rice (Republican) 35.6%
Stella Sollars (Independent) 1.6% |
| Missouri|6|X}} | William Raleigh Hull Jr. | Democratic | 1954 | Incumbent retired.
New member elected.
Democratic hold. | √ Jerry Litton (Democratic) 54.6%
Russell Sloan (Republican) 45.4% |
| Missouri|7|X}} | Durward Gorham Hall | Republican | 1960 | Incumbent retired.
New member elected.
Republican hold. | √ Gene Taylor (Republican) 63.7%
Bill Thomas (Democratic) 36.3% |
| Missouri|8|X}} | Richard Howard Ichord Jr. | Democratic | 1960 | Incumbent re-elected. | √ Richard Howard Ichord Jr. (Democratic) 62.1%
David R. Countie (Republican) 37.9% |
| Missouri|9|X}} | William L. Hungate | Democratic | 1964 | Incumbent re-elected. | √ William L. Hungate (Democratic) 66.5%
Robert L. Prange (Republican) 33.5% |
| Missouri|10|X}} | Bill Burlison | Democratic | 1968 | Incumbent re-elected. | √ Bill Burlison (Democratic) 64.3%
Marion Francis Svendrowski (Republican) 35.7% |