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词条 Capillin
释义

  1. Chemical taxonomy

  2. Applications

{{Chembox
| ImageFile = Capilline.png
| ImageSize = 200px
| ImageAlt =
| IUPACName = 1-phenylhexa-2,4-diyn-1-one
| OtherNames = Capillin
| Section1 = {{Chembox Identifiers
| CASNo = 495-74-9
| PubChem = 10321
| ChemSpiderID = 9899
| EINECS =
| SMILES = CC#CC#CC(=O)C1=CC=CC=C1
| StdInChI= 1S/C12H8O/c1-2-3-5-10-12(13)11-8-6-4-7-9-11/h4,6-9H,1H3
| StdInChIKey= RAZOKRUZEQERLH-UHFFFAOYSA-N
| Section2 = {{Chembox Properties
| C=12|H=8|O=1
| Appearance =
| Density =
| Solubility = 0.0177 mg/mL
| MeltingPt = 82–83 °C
| BoilingPt =
| VaporPressure =
| Section3 = {{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}

Capillin is a naturally occurring organic compound with the chemical formula {{chem|C|12|H|8|O}}. The structure contains acetophenone and a polyyne portions, conjugated together as an ynone.

Chemical taxonomy

Capillin is found in the essential oil of a number of Artemisia species, including Artemisia monosperma and Artemisia dracunculus (tarragon).[1] The substance was initially isolated from Artemisia capillaris in 1956.[2]

Applications

Capillin is a biologically active substance. It has strong antifungal activity, and it is possibly antitumoral. Capillin exhibits cytotoxic activity and could cause apoptosis of certain human tumor cells.[3]

1. ^{{cite web|title=Showing metabocard for Capillin (HMDB32867)|url=http://www.hmdb.ca/metabolites/HMDB32867|website=Human Metabolome Database|publisher=hmdb.ca|accessdate=17 May 2017}}
2. ^{{cite journal|last1=Nash|first1=B. W.|last2=Thomas|first2=D. A.|last3=Warburton|first3=W. K.|last4=Williams|first4=Thelma D.|title=535. The preparation of capillin and some related compounds, and of some substituted pent-4-en-2-yn-1-ones|journal=J. Chem. Soc.|date=1965|pages=2983–2988|doi=10.1039/JR9650002983}}
3. ^{{cite journal |vauthors = Whelan LC, Ryan MF |title = Effects of the polyacetylene capillin on human tumour cell lines |journal = Anticancer Research |volume = 24 |issue = 4 |pages = 2281–6 |year = 2004 |pmid = 15330173}}

2 : Aromatic ketones|Alkynes

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