词条 | Ciprocinonide |
释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = 2-[(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-4b,12-Difluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]-2-oxoethyl cyclopropanecarboxylate | image = Ciprocinonide.svg | width = | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 58524-83-7 | CAS_supplemental = | class = Corticosteroid; Glucocorticoid | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 11954352 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = | UNII = 8Y88CP83MK | KEGG = D03520 | ChEBI = | ChEMBL = 2105934 | C=28 | H=34 | F=2 | O=7 | SMILES = C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)COC(=O)C5CC5)C[C@@H](C6=CC(=O)C=C[C@@]63C)F)F)O | StdInChI_Ref = | StdInChI = 1S/C28H34F2O7/c1-24(2)36-22-11-16-17-10-19(29)18-9-15(31)7-8-25(18,3)27(17,30)20(32)12-26(16,4)28(22,37-24)21(33)13-35-23(34)14-5-6-14/h7-9,14,16-17,19-20,22,32H,5-6,10-13H2,1-4H3/t16-,17-,19-,20-,22+,25-,26-,27-,28+/m0/s1 | StdInChIKey_Ref = | StdInChIKey = TZBDXWBBMOEVPI-XBQQDWOSSA-N | synonyms = RS-2386; Fluocinolone acetonide 21-cyclopropylcarboxylate; 6α,9α-Difluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone 21-cyclopropanecarboxylate; 6α,9α-Difluoro-11β,21-dihydroxy-16α,17α-((1-methylethylidene)bis(oxy))pregna-1,4-diene-3,20-dione 21-cyclopropanecarboxylate }}Ciprocinonide (developmental code name RS-2386), also known as fluocinolone acetonide cyclopropylcarboxylate, is a synthetic glucocorticoid corticosteroid which was never marketed.[1] References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA282|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=282–}} {{Glucocorticoid receptor modulators}}{{steroid-stub}} 9 : Acetonides|Alcohols|Carboxylic acids|Corticosteroid cyclic ketals|Corticosteroid esters|Cyclopropanes|Fluoroarenes|Glucocorticoids|Pregnanes |
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