词条 | Clostebol caproate |
释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = (1S,2R,10R,11S,14S,15S)-6-Chloro-2,15-dimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-14-yl hexanoate | image = Clostebol caproate.svg | width = 250px | image2 = Clostebol caproate molecule ball.png | width2 = 250px | tradename = Macrobin-Depot | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Intramuscular injection | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 32361-10-7 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 8246328 | UNII = | KEGG = | ChEBI = | ChEMBL = | C=25 | H=37 | Cl=1 | O=3 | molecular_weight = 421.019 g/mol | SMILES = CCCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=C(Cl)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C | StdInChI_Ref = | StdInChI = 1S/C25H37ClO3/c1-4-5-6-7-22(28)29-21-11-10-17-16-8-9-19-23(26)20(27)13-15-24(19,2)18(16)12-14-25(17,21)3/h16-18,21H,4-15H2,1-3H3/t16-,17-,18-,21-,24?,25?/m0/s1 | StdInChIKey_Ref = | StdInChIKey = OMNUNHQDARKLSM-VPKDWVKTSA-N | synonyms = }}Clostebol caproate (brand name Macrobin-Depot), also known as clostebol hexanoate or chlorotestosterone caproate (JAN), as well as 4-chlorotestosterone 17β-caproate or as 4-chloroandrost-4-en-17β-ol-3-one 17β-caproate, is a synthetic, injected anabolic-androgenic steroid (AAS) and a derivative of testosterone.[1][2] It is an androgen ester – specifically, the C17β caproate ester of clostebol (4-chlorotestosterone) – and acts as a prodrug of clostebol in the body.[1]{{Additional citation needed|date=November 2016}} Clostebol acetate is administered via intramuscular injection.[2] See also
References1. ^1 {{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA305|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=305–}} {{Androgens and antiandrogens}}{{Androgen receptor modulators}}{{steroid-stub}}{{genito-urinary-drug-stub}}2. ^1 {{cite book|author1=I.K. Morton|author2=Judith M. Hall|title=Concise Dictionary of Pharmacological Agents: Properties and Synonyms|url=https://books.google.com/books?id=mqaOMOtk61IC&pg=PA80|date=31 October 1999|publisher=Springer Science & Business Media|isbn=978-0-7514-0499-9|pages=80–}} 8 : Alcohols|Androgen esters|Androgens and anabolic steroids|Androstanes|Caproate esters|Organochlorides|Prodrugs|World Anti-Doping Agency prohibited substances |
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