请输入您要查询的百科知识:

 

词条 DECIPHER (software)
释义

  1. Features

  2. See also

  3. References

  4. External links

{{Infobox software
| name = DECIPHER
| logo =
| screenshot =
| caption =
| developer = Erik Wright
| released =
| latest release version = 2.10.0
| latest release date = {{Start date|2018}}
| latest preview version =
| latest preview date =
| status = Active
|programming language = R, C
| operating system = Unix, Linux, macOS, Windows
| platform = IA-32, x86-64
| size =
| language = English
| genre = Bioinformatics
| license = GPL 3
| website = {{URL|decipher.codes}}
}}

DECIPHER is a software toolset that can be used to decipher and manage biological sequences efficiently using the programming language R. Some functions of the program are accessible online through web tools.

Features

  • Sequence databases: import, maintain, view, and export sequences.
  • Multiple sequence alignment: align sequences of DNA, RNA, or amino acids.[1]
  • Genome alignment: find and align the syntenic regions of multiple genomes.
  • Oligonucleotide design:[2] primer design[3][4] for polymerase chain reaction (PCR), probe design for fluorescence in situ hybridization (FISH)[5] or DNA microarrays.[6]
  • Manipulate sequences: trim low quality regions, correct frameshifts, reorient nucleotides, determine consensus, or digest with restriction enzymes.
  • Analyze sequences: find chimeras,[7] predict secondary structure, classify into a taxonomy,[8] and create phylogenetic trees.

See also

{{Div col|colwidth=22em}}
  • Sequence alignment software
{{div col end}}

References

1. ^{{cite journal |author=Wright ES |title=DECIPHER: harnessing local sequence context to improve protein multiple sequence alignment |journal=BMC Bioinformatics |year=2015 |pmid=26445311 |doi=10.1186/s12859-015-0749-z |volume=16 |pmc=4595117 |pages=322}}
2. ^{{cite journal |vauthors=Noguera DR, Wright ES, Camejo P, Yilmaz LS |title=Mathematical tools to optimize the design of oligonucleotide probes and primers |journal=Applied Microbiology and Biotechnology |year=2014 |pmid=25359473 |doi=10.1007/s00253-014-6165-x |volume=98 |pages=9595–608}}
3. ^{{cite journal |vauthors=Wright ES, Yilmaz LS, Ram S, Gasser JM, Harrington GW, Noguera DR |title=Exploiting extension bias in polymerase chain reaction to improve primer specificity in ensembles of nearly identical DNA templates |journal=Environmental Microbiology |volume= 16|issue=5 |pages=1354–1365 |year=2014 |pmid=24750536 |doi=10.1111/1462-2920.12259}}
4. ^{{cite journal |vauthors=Wright ES, Vetsigian KH |title=DesignSignatures: a tool for designing primers that yields amplicons with distinct signatures |journal=Bioinformatics |volume=32 |issue=10 |pages=1565–1567 |year=2016 |pmid=26803162 |doi=10.1093/bioinformatics/btw047}}
5. ^{{cite journal |vauthors=Wright ES, Yilmaz LS, Corcoran AM, Okten HE, Noguera DR |title=Automated Design of Probes for rRNA-Targeted Fluorescence In Situ Hybridization Reveals the Advantages of Using Dual Probes for Accurate Identification |journal=Applied and Environmental Microbiology |volume=80 |issue=16 |pages=5124–5133 |year=2014 |pmid=24928876 |doi=10.1128/AEM.01685-14 |pmc=4135741}}
6. ^{{cite journal |vauthors=Yilmaz LS, Loy A, Wright ES, Wagner M, Noguera DR |title=Modeling formamide denaturation of probe-target hybrids for improved microarray probe design in microbial diagnostics |journal=PLOS ONE |year=2012 |pmid=22952791 |doi=10.1371/journal.pone.0043862 |volume=7 |pmc=3428302 |pages=e43862}}
7. ^{{cite journal |vauthors=Wright ES, Yilmaz LS, Noguera DR |title=DECIPHER, a search-based approach to chimera identification for 16S rRNA sequences |journal=Applied and Environmental Microbiology |volume=78 |issue=3 |pages=717–725 |year=2012 |pmid=22101057 |doi=10.1128/AEM.06516-11 |pmc=3264099}}
8. ^{{cite journal |vauthors=Murali A, Bhargava A, Wright ES |title=IDTAXA: a novel approach for accurate taxonomic classification of microbiome sequences |journal=Microbiome |volume=6 |issue=140 |year=2018 |doi=10.1186/s40168-018-0521-5}}

External links

  • {{Official website|decipher.codes}}
{{science-software-stub}}

2 : Bioinformatics software|Computational phylogenetics

随便看

 

开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。

 

Copyright © 2023 OENC.NET All Rights Reserved
京ICP备2021023879号 更新时间:2024/11/16 4:01:32