词条 | Doxibetasol |
释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = (8S,9R,10S,11S,13S,14S,16S,17R)-17-Acetyl-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one | image = Doxibetasol.svg | width = | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 1879-77-2 | CAS_supplemental = | class = Corticosteroid; Glucocorticoid | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 71106 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = | UNII = 0JS043FG0D | KEGG = | ChEBI = | ChEMBL = | C=22 | H=29 | F=1 | O=4 | SMILES = C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)C)O)C)O)F)C | StdInChI_Ref = | StdInChI = 1S/C22H29FO4/c1-12-9-17-16-6-5-14-10-15(25)7-8-19(14,3)21(16,23)18(26)11-20(17,4)22(12,27)13(2)24/h7-8,10,12,16-18,26-27H,5-6,9,11H2,1-4H3/t12-,16-,17-,18-,19-,20-,21-,22-/m0/s1 | StdInChIKey_Ref = | StdInChIKey = IKGBPSZWCRRUQS-DTAAKRQUSA-N | synonyms = Doxybetasol; Deoxydexamethasone; 21-Deoxydexamethasone; GR 2/443; 9α-Fluoro-11β,17α-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione }}Doxibetasol (doxybetasol; developmental code name GR 2/443) is a synthetic glucocorticoid corticosteroid.[1] References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA470|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=470–}} {{Glucocorticoid receptor modulators}}{{steroid-stub}} 5 : Diketones|Diols|Fluoroarenes|Glucocorticoids|Pregnanes |
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