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词条 Doxibetasol
释义

  1. References

{{Drugbox
| Verifiedfields =
| Watchedfields =
| verifiedrevid =
| IUPAC_name = (8S,9R,10S,11S,13S,14S,16S,17R)-17-Acetyl-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
| image = Doxibetasol.svg
| width =
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref =
| CAS_number = 1879-77-2
| CAS_supplemental =
| class = Corticosteroid; Glucocorticoid
| ATC_prefix =
| ATC_suffix =
| ATC_supplemental =
| PubChem = 71106
| IUPHAR_ligand =
| DrugBank_Ref =
| DrugBank =
| ChemSpiderID_Ref =
| ChemSpiderID =
| UNII = 0JS043FG0D
| KEGG =
| ChEBI =
| ChEMBL =
| C=22 | H=29 | F=1 | O=4
| SMILES = C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)C)O)C)O)F)C
| StdInChI_Ref =
| StdInChI = 1S/C22H29FO4/c1-12-9-17-16-6-5-14-10-15(25)7-8-19(14,3)21(16,23)18(26)11-20(17,4)22(12,27)13(2)24/h7-8,10,12,16-18,26-27H,5-6,9,11H2,1-4H3/t12-,16-,17-,18-,19-,20-,21-,22-/m0/s1
| StdInChIKey_Ref =
| StdInChIKey = IKGBPSZWCRRUQS-DTAAKRQUSA-N
| synonyms = Doxybetasol; Deoxydexamethasone; 21-Deoxydexamethasone; GR 2/443; 9α-Fluoro-11β,17α-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione
}}Doxibetasol (doxybetasol; developmental code name GR 2/443) is a synthetic glucocorticoid corticosteroid.[1]

References

1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA470|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=470–}}
{{Glucocorticoid receptor modulators}}{{steroid-stub}}

5 : Diketones|Diols|Fluoroarenes|Glucocorticoids|Pregnanes

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