词条 | Draft:Jan Huisken |
释义 |
Jan Huisken (born 26 November 1974 in Göttingen, Germany) is a German physicist. Since 2016, he has been a principal investigator and leader of the Medical Engineering theme in the Morgridge Institute for Research at the University of Wisconsin, Madison. Huisken is considered a co-founder of modern light sheet microscopy and received the Medal for Light Microscopy 2017 from the Royal Microscopical Society (RMS)[1] for his outstanding work. LifeHuisken studied Physics at Göttingen University and Heidelberg University. Subsequently, he was a doctoral candidate in the International PhD Program of the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. From 2000 until 2004 he worked on optical tweezers and high-resolution fluorescence microscopy in the lab of Ernst H.K. Stelzer. His work focused primarily on multidimensional light sheet microscopy (also Selective Plane Illumination Microscopy, SPIM) and its applications in the life sciences. Huisken completed this work by receiving a doctoral degree in 2004 from Freiburg University. For one of the first applications of light sheet microscopy, Huisken turned his attention towards Medaka development in the lab of Joachim Wittbrodt.[2] Huisken moved to San Francisco in 2005 for a postdoctoral Human Frontier Science Program (HFSP) fellowship in the lab of Didier Y.R. Stainier at the University of California. Using his self-engineered microscope, he researched cardiovascular morphogenesis and function in zebrafish.[3] Huisken achieved key breakthroughs in the application of multidimensional in vivo fluorescence imaging to become an internationally recognized microscope developer and cross-disciplinary biophysicist. From 2010 until 2016 Huisken was an independent group leader at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany. Additionally, in 2013 he joined the Center for Systems Biology in Dresden. He has been a principal investigator and leader of the Medical Engineering theme at the Morgridge Institute for Research at the University of Wisconsin in Madison since 2016. Since 2018 he is also a Visiting Professor in the Department of Integrative Biology at the University of Wisconsin. Huisken is married and has two children. Awards
Literature
Selected Publications
References1. ^{{Cite web|url=https://www.rms.org.uk/discover-engage/competitions-awards/rms-medal-series.html|title=Medal Series|last=Mel|website=www.rms.org.uk|access-date=2018-10-21}} 2. ^{{Cite journal|last=Huisken|first=Jan|last2=Swoger|first2=Jim|last3=Bene|first3=Filippo Del|last4=Wittbrodt|first4=Joachim|last5=Stelzer|first5=Ernst H. K.|date=2004-08-13|title=Optical Sectioning Deep Inside Live Embryos by Selective Plane Illumination Microscopy|url=http://science.sciencemag.org/content/305/5686/1007|journal=Science|language=en|volume=305|issue=5686|pages=1007–1009|doi=10.1126/science.1100035|issn=0036-8075|pmid=15310904|citeseerx=10.1.1.456.2250}} 3. ^{{Cite journal|last=Huisken|first=Jan|last2=Stainier|first2=Didier Y. R.|date=2007-09-01|title=Even fluorescence excitation by multidirectional selective plane illumination microscopy (mSPIM)|url=https://www.osapublishing.org/ol/abstract.cfm?uri=ol-32-17-2608|journal=Optics Letters|language=EN|volume=32|issue=17|pages=2608–2610|doi=10.1364/OL.32.002608|issn=1539-4794}} 4. ^{{Cite web|url=https://www.rms.org.uk/discover-engage/competitions-awards/rms-medal-series.html|title=Medal Series|last=Mel|website=www.rms.org.uk|access-date=2018-10-21}} 5. ^{{Cite news|url=https://erc.europa.eu/projects-figures/erc-funded-projects/results?search_api_views_fulltext=&page=131&items_per_page=10&f%5B0%5D=funding_scheme:Consolidator%20Grant%20(CoG)|title=ERC FUNDED PROJECTS|work=ERC: European Research Council|access-date=2018-10-21|language=en}} 6. ^{{Cite news|url=http://www.embo.org/news/press-releases/2014/twenty-seven-researchers-named-as-embo-young-investigators|title=Twenty-seven researchers named as EMBO Young Investigators|last=User|first=Super|work=EMBO|access-date=2018-10-21|language=en-gb}} 7. ^{{Cite news|url=https://www.engr.wisc.edu/novel-data-storage-project-unshackles-microscopy-data-overload/|title=A novel data storage project unshackles microscopy from data overload - College of Engineering - University of Wisconsin-Madison|date=2017-10-19|work=College of Engineering - University of Wisconsin-Madison|access-date=2018-10-21|language=en-US}} 8. ^{{Cite news|url=https://morgridge.org/story/jan-huisken-building-a-better-smarter-microscope/|title=Jan Huisken: Building a better, smarter microscope|access-date=2018-10-21|language=en-US}} 9. ^{{Cite news|url=https://www.engr.wisc.edu/focus-new-faculty-jan-huisken-developing-new-tools-biological-imaging/|title=Focus on new faculty: Jan Huisken, developing new tools for biological imaging - College of Engineering - University of Wisconsin-Madison|date=2016-03-12|work=College of Engineering - University of Wisconsin-Madison|access-date=2018-10-21|language=en-US}} 10. ^{{Cite news|url=https://morgridge.org/story/new-research-team-leader-foresees-era-of-smart-microscopes/|title=New Morgridge research team leader foresees era of ‘smart microscopes’|access-date=2018-10-21|language=en-US}} 11. ^{{Cite web|url=https://www.mpg.de/8313107/herz_zebrafisch_3d|title=Herzschlag in 3D|website=www.mpg.de|language=de|access-date=2018-10-21}} 12. ^{{Cite web|url=https://www.oxinst.com/learning/view/article/fundamentals-of-embryo-development-uncovered-in-real-time|title=Fundamentals of Embryo Development uncovered in real time - Andor Learning Centre|website=Oxford Instruments|language=en-GB|access-date=2018-10-21}} 13. ^{{Cite journal|last=Power|first=Rory|title=A guide to light-sheet fluorescence microscopy for multiscale imaging|url=https://www.nature.com/articles/nmeth.4224#article-info|journal=Nature Methods|volume=14|issue=4|pages=360–373|via=|doi=10.1038/nmeth.4224|pmid=28362435|year=2017}} 14. ^{{Cite journal|last=Jahr|first=Wiebke|last2=Schmid|first2=Benjamin|last3=Schmied|first3=Christopher|last4=Fahrbach|first4=Florian O.|last5=Huisken|first5=Jan|date=2015-09-02|title=Hyperspectral light sheet microscopy|url=http://www.nature.com/articles/ncomms8990|journal=Nature Communications|language=En|volume=6|issue=1|pages=7990|doi=10.1038/ncomms8990|issn=2041-1723|pmc=4569691|pmid=26329685}} 15. ^{{Cite journal|last=Scherf|first=Nico|last2=Huisken|first2=Jan|date=August 2015|title=The smart and gentle microscope|url=http://www.nature.com/articles/nbt.3310|journal=Nature Biotechnology|language=En|volume=33|issue=8|pages=815–818|doi=10.1038/nbt.3310|pmid=26252136|issn=1087-0156}} 16. ^{{Cite journal|last=Bassi|first=Andrea|last2=Schmid|first2=Benjamin|last3=Huisken|first3=Jan|date=2015-03-01|title=Optical tomography complements light sheet microscopy for in toto imaging of zebrafish development|url=http://dev.biologists.org/content/142/5/1016|journal=Development|language=en|volume=142|issue=5|pages=1016–1020|doi=10.1242/dev.116970|issn=0950-1991|pmc=4352980|pmid=25655702}} 17. ^{{Cite journal|last=Mickoleit|first=Michaela|last2=Schmid|first2=Benjamin|last3=Weber|first3=Michael|last4=Fahrbach|first4=Florian O|last5=Hombach|first5=Sonja|last6=Reischauer|first6=Sven|last7=Huisken|first7=Jan|date=2014-07-20|title=High-resolution reconstruction of the beating zebrafish heart|url=http://www.nature.com/articles/nmeth.3037|journal=Nature Methods|language=En|volume=11|issue=9|pages=919–922|doi=10.1038/nmeth.3037|pmid=25042787|issn=1548-7091}} 18. ^{{Cite journal|last=Schmid|first=Benjamin|last2=Shah|first2=Gopi|last3=Scherf|first3=Nico|last4=Weber|first4=Michael|last5=Thierbach|first5=Konstantin|last6=Campos|first6=Citlali Pérez|last7=Roeder|first7=Ingo|last8=Aanstad|first8=Pia|last9=Huisken|first9=Jan|date=2013-07-25|title=High-speed panoramic light-sheet microscopy reveals global endodermal cell dynamics|url=http://www.nature.com/articles/ncomms3207|journal=Nature Communications|language=En|volume=4|issue=1|pages=2207|doi=10.1038/ncomms3207|issn=2041-1723|pmc=3731668|pmid=23884240}} 19. ^{{Cite journal|last=Kaufmann|first=Anna|last2=Mickoleit|first2=Michaela|last3=Weber|first3=Michael|last4=Huisken|first4=Jan|date=2012-09-01|title=Multilayer mounting enables long-term imaging of zebrafish development in a light sheet microscope|url=http://dev.biologists.org/content/139/17/3242|journal=Development|language=en|volume=139|issue=17|pages=3242–3247|doi=10.1242/dev.082586|issn=0950-1991|pmid=22872089}} 20. ^{{Cite journal|last=Arrenberg|first=Aristides B.|last2=Stainier|first2=Didier Y. R.|last3=Baier|first3=Herwig|last4=Huisken|first4=Jan|date=2010-11-12|title=Optogenetic Control of Cardiac Function|url=http://science.sciencemag.org/content/330/6006/971|journal=Science|language=en|volume=330|issue=6006|pages=971–974|doi=10.1126/science.1195929|issn=0036-8075|pmid=21071670}} 21. ^{{Cite journal|last=Herbert|first=Shane P.|last2=Huisken|first2=Jan|last3=Kim|first3=Tyson N.|last4=Feldman|first4=Morri E.|last5=Houseman|first5=Benjamin T.|last6=Wang|first6=Rong A.|last7=Shokat|first7=Kevan M.|last8=Stainier|first8=Didier Y. R.|date=2009-10-09|title=Arterial-Venous Segregation by Selective Cell Sprouting: An Alternative Mode of Blood Vessel Formation|url=http://science.sciencemag.org/content/326/5950/294|journal=Science|language=en|volume=326|issue=5950|pages=294–298|doi=10.1126/science.1178577|issn=0036-8075|pmc=2865998|pmid=19815777}} 22. ^{{Cite journal|last=Huisken|first=Jan|last2=Stainier|first2=Didier Y. R.|date=2009-06-15|title=Selective plane illumination microscopy techniques in developmental biology|url=http://dev.biologists.org/content/136/12/1963|journal=Development|language=en|volume=136|issue=12|pages=1963–1975|doi=10.1242/dev.022426|issn=0950-1991|pmc=2685720|pmid=19465594}} 23. ^{{Cite journal|last=Huisken|first=Jan|last2=Stainier|first2=Didier Y. R.|date=2007-09-01|title=Even fluorescence excitation by multidirectional selective plane illumination microscopy (mSPIM)|url=https://www.osapublishing.org/ol/abstract.cfm?uri=ol-32-17-2608|journal=Optics Letters|language=EN|volume=32|issue=17|pages=2608–2610|doi=10.1364/OL.32.002608|issn=1539-4794}} 24. ^{{Cite journal|last=Huisken|first=Jan|last2=Swoger|first2=Jim|last3=Bene|first3=Filippo Del|last4=Wittbrodt|first4=Joachim|last5=Stelzer|first5=Ernst H. K.|date=2004-08-13|title=Optical Sectioning Deep Inside Live Embryos by Selective Plane Illumination Microscopy|url=http://science.sciencemag.org/content/305/5686/1007|journal=Science|language=en|volume=305|issue=5686|pages=1007–1009|doi=10.1126/science.1100035|issn=0036-8075|pmid=15310904|citeseerx=10.1.1.456.2250}} |
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