“2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase”的意思、由来-开放百科全书

词条

2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase

释义

References

{{enzyme
| Name = 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase
| EC_number = 1.3.1.58
| CAS_number =
| IUBMB_EC_number = 1/3/1/58
| GO_code = 0018511
| image =
| width =
| caption =
}}

In enzymology, a 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase ({{EC number|1.3.1.58}}) is an enzyme that catalyzes the chemical reaction

cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate + NAD⁺ 2,3-dihydroxy-p-cumate + NADH + H⁺

Thus, the two substrates of this enzyme are cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate and NAD⁺, whereas its 3 products are 2,3-dihydroxy-p-cumate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-2,3-dihydroxy-2,3-dihydro-p-cumate:NAD+ oxidoreductase. This enzyme participates in biphenyl degradation.

References

{{cite journal | author = Eaton RW | date = 1996 | title = p-Cumate catabolic pathway in Pseudomonas putida Fl: cloning and characterization of DNA carrying the cmt operon | journal = J. Bacteriol. | volume = 178 | pages = 1351–62 | pmid = 8631713 | issue = 5 | pmc = 177810 }}

3 : EC 1.3.1|NADH-dependent enzymes|Enzymes of unknown structure

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