“2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase”的意思、由来-开放百科全书

词条

2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase

释义

References

{{enzyme
| Name = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase
| EC_number = 1.3.1.40
| CAS_number = 104645-83-2
| IUBMB_EC_number = 1/3/1/40
| GO_code = 0047118
| image =
| width =
| caption =
}}

In enzymology, a 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase ({{EC number|1.3.1.40}}) is an enzyme that catalyzes the chemical reaction

2,6-dioxo-6-phenylhexanoate + NADP⁺ 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + NADPH + H⁺

Thus, the two substrates of this enzyme are 2,6-dioxo-6-phenylhexanoate and NADP⁺, whereas its 3 products are 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2,6-dioxo-6-phenylhexanoate:NADP+ Delta2-oxidoreductase. Other names in common use include 2-hydroxy-6-oxo-phenylhexa-2,4-dienoate (reduced nicotinamide, and adenine dinucleotide phosphate) reductase.

References

{{cite journal |vauthors=Omori T, Ishigooka H, Minoda Y | date = 1986 | title = Purification and some properties of 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid(HOPDA) reducing enzyme from Pseudomonas cruciviae S93B1 involved in the degradation of biphenyl | journal = Agric. Biol. Chem. | volume = 50 | pages = 1513–1518 | doi=10.1271/bbb1961.50.1513}}

3 : EC 1.3.1|NADPH-dependent enzymes|Enzymes of unknown structure

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