| 释义 |
- Function General transport reaction
- References
- Further reading
{{Pfam box|Symbol=LctP|Name=Lactate permease|image=|width=|caption=|Pfam=PF02652|Pfam_clan=|InterPro=IPR003804|SMART=|PROSITE=|SCOP=|TCDB=2.A.14|OPM family=|OPM protein=|PDB=}}The lactate permease (LctP) family (TC# 2.A.14) is a family of transport proteins belonging to the ion transporter (IT) superfamily.[1] Function Characterized members of this family possess 15-18 transmembrane segments (TMSs) and are roughly 460-565 amino acyl residues in length. General transport reaction Transport reactions catalyzed by functionally characterized members of the LctP family include:[2] D- or L-lactate or glycolate (out) + H+ (out) → D- or L-lactate or glycolate (in) + H+ (in). References 1. ^{{cite journal | vauthors = Prakash S, Cooper G, Singhi S, Saier MH | title = The ion transporter superfamily | journal = Biochimica et Biophysica Acta | volume = 1618 | issue = 1 | pages = 79–92 | date = December 2003 | pmid = 14643936 | doi = 10.1016/j.bbamem.2003.10.010 }}
2. ^{{Cite web|url=http://www.tcdb.org/search/result.php?tc=2.A.14|title=2.A.14 The Lactate Permease (LctP) Family|website=Transporter Classification Database|access-date=2016-03-02}}
Further reading {{refbegin}}- {{cite journal | vauthors = Moraes TF, Reithmeier RA | title = Membrane transport metabolons | journal = Biochimica et Biophysica Acta | volume = 1818 | issue = 11 | pages = 2687–706 | date = November 2012 | pmid = 22705263 | doi = 10.1016/j.bbamem.2012.06.007 }}
- {{cite journal | vauthors = Núñez MF, Kwon O, Wilson TH, Aguilar J, Baldoma L, Lin EC | title = Transport of L-Lactate, D-Lactate, and glycolate by the LldP and GlcA membrane carriers of Escherichia coli | journal = Biochemical and Biophysical Research Communications | volume = 290 | issue = 2 | pages = 824–9 | date = January 2002 | pmid = 11785976 | doi = 10.1006/bbrc.2001.6255 }}
- {{cite journal | vauthors = Rabus R, Jack DL, Kelly DJ, Saier MH | title = TRAP transporters: an ancient family of extracytoplasmic solute-receptor-dependent secondary active transporters | journal = Microbiology | volume = 145 | issue = 12 | pages = 3431–45 | date = December 1999 | pmid = 10627041 | doi = 10.1099/00221287-145-12-3431 }}
- {{cite journal | vauthors = Saier MH, Eng BH, Fard S, Garg J, Haggerty DA, Hutchinson WJ, Jack DL, Lai EC, Liu HJ, Nusinew DP, Omar AM, Pao SS, Paulsen IT, Quan JA, Sliwinski M, Tseng TT, Wachi S, Young GB | title = Phylogenetic characterization of novel transport protein families revealed by genome analyses | journal = Biochimica et Biophysica Acta | volume = 1422 | issue = 1 | pages = 1–56 | date = February 1999 | pmid = 10082980 }}
{{refend}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{Dual|sourcepath=http://www.tcdb.org/search/result.php?tc=2.A.14|sourcearticle=2.A.14 The Lactate Permease (LctP) Family|source=Transporter Classification Database|date=12 March 2016}} 2 : Protein families|Solute carrier family |