词条 | NuGEN Technologies |
释义 |
| name = NuGEN Technologies, Inc | logo = | logo_padding = | logo_alt = | logo_caption = | image = | image_size = | image_alt = | image_caption = | trading_name = | native_name = | romanized_name = | type = Privately | traded_as = | ISIN = | industry = Biotechnology | genre = | fate = | predecessor = | successor = | founded = 2000 | founders = | defunct = | hq_location = | hq_location_city = San Carlos, California | hq_location_country = United States | num_locations = | num_locations_year = | area_served = | key_people = Nitin Sood, CEO | products = | brands = | production = | production_year = | services = | revenue = | revenue_year = | operating_income = | parent = | divisions = | subsid = | module = | website = {{URL|http://www.nugen.com/}} | footnotes = | intl = | coordinates = | slogan = }}NuGEN Technologies, Inc. is a US based biotech company located in San Carlos, California, founded in 2000 by Nurith Kurn. NuGEN Technologies develops and manufactures molecular biology reagents for next-generation sequencing genomic analysis. The company is currently led by CEO Nitin Sood. NuGEN Technologies currently holds several U.S. patents including SPIA, AnyDeplete, DimerFree, and SPET.[1][2] OverviewNuGEN Technologies provides next-generation sequencing (NGS) sample prep reagents for DNA-Seq, whole transcriptome RNA-Seq,[3] mRNA-Seq,[4] Methyl-Seq,[5][6] and Targeted SNP genotyping.[7] NuGEN technologies provides products that work with different sample types including fresh, frozen, cell-free DNA and RNA, FFPE, laser capture microdissection, and liquid biopsy.[8] NuGEN provides Unique Dual Indexes with specific products to enable researchers to identify barcode hopping, a problem identified with Illumina sequencers.[9] NuGEN's products have been the basis for studies published in scientific publications, such as Nature,[10] Cell,[11] Neuron,[12] Blood,[13] eLife,[14] PLoS One,[15] PNAS,[16] and Infection and Immunity.[17] In 2017, NuGEN Technologies partnered with Cambridge Epigenetics to provide True-Methyl oxBS technology with their Methyl-Seq and RRBS Methyl-Seq library prep kits.[18] References1. ^{{cite web|url=https://www.biotechniques.com/biomarket/company/NuGen-Technologies/biotechniques-114857.html|title=BioTechniques - NuGen Technologies|website=www.biotechniques.com|accessdate=2 October 2017}} 2. ^{{cite web|url=https://www.benzinga.com/pressreleases/14/04/b4494254/nugens-novel-technology-for-rna-seq-extends-to-a-broad-range-of-transcr|title=NuGEN's Novel Technology for RNA-Seq Extends to a Broad Range of Transcript Species|website=Benzinga|accessdate=2 October 2017}} 3. ^{{cite web|url=http://www.genengnews.com/webinars/get-rid-of-the-noise-targeted-depletion-approach-for-rna-seq/278|title=Get Rid of the Noise: Targeted Depletion Approach for RNA-Seq {{!}} GEN|website=GEN|accessdate=2 October 2017}} 4. ^{{cite web|url=https://www.genomeweb.com/new-products-posted-genomeweb-week-diatech-pharmacogenetics-helix-helomics-and-nugen-technologies|title=New Products Posted to GenomeWeb This Week: Diatech Pharmacogenetics, Helix, Helomics, and NuGen Technologies|website=GenomeWeb|language=en|accessdate=2 October 2017}} 5. ^{{cite web|url=https://www.technologynetworks.com/genomics/news/cambridge-epigenetix-and-nugen-technologies-sign-agreement-to-combine-technologies-in-epigenetics-291146|title=Cambridge Epigenetix, NuGEN Technologies Sign Agreement to Combine Leading Technologies in Epigenetics Research|website=Genomics Research from Technology Networks|accessdate=2 October 2017}} 6. ^{{cite web|pmc=5065634|title=High concordance between Illumina HiSeq2500 and NextSeq500 for reduced representation bisulfite sequencing (RRBS)|last1=Yin|first1=Danqing|last2=Ritchie|first2=Matthew E.|date=6 October 2016|website=Genomics Data|pages=97–100|doi=10.1016/j.gdata.2016.10.002|accessdate=2 October 2017|last3=Jabbari|first3=Jafar S.|last4=Beck|first4=Tamara|last5=Blewitt|first5=Marnie E.|last6=Keniry|first6=Andrew}} 7. ^{{Cite news|url=https://www.genomeweb.com/pcrsample-prep/product-watch-identigen-snp-genotyping-assay-chemistry-nugen-target-enrichment|title=Product Watch: IdentiGen SNP Genotyping Assay Chemistry; NuGen Target Enrichment|work=GenomeWeb|access-date=2017-11-03|language=en}} 8. ^{{cite web|url=https://www.genomeweb.com/sequencing/circulating-tumor-dna-shorter-circulating-normal-dna-study-finds|title=Circulating Tumor DNA Shorter Than Circulating Normal DNA, Study Finds|website=GenomeWeb|language=en|accessdate=2 October 2017}} 9. ^{{Cite web|url=http://dnatech.genomecenter.ucdavis.edu/2017/04/11/update-on-barcode-mis-assignment-issue/|title=Update on Barcode Mis-Assignment Issue {{!}} DNA Technologies Core|website=dnatech.genomecenter.ucdavis.edu|language=en-US|access-date=2017-11-03}} 10. ^{{Cite journal|last=Chung|first=Shinjae|last2=Weber|first2=Franz|last3=Zhong|first3=Peng|last4=Tan|first4=Chan Lek|last5=Nguyen|first5=Thuc Nghi|last6=Beier|first6=Kevin T.|last7=Hörmann|first7=Nikolai|last8=Chang|first8=Wei-Cheng|last9=Zhang|first9=Zhe|date=2017-05-17|title=Identification of preoptic sleep neurons using retrograde labelling and gene profiling|url=https://www.nature.com/articles/nature22350|journal=Nature|language=en|volume=545|issue=7655|pages=nature22350|doi=10.1038/nature22350}} 11. ^{{Cite journal|last=Latil|first=Mathilde|last2=Nassar|first2=Dany|last3=Beck|first3=Benjamin|last4=Boumahdi|first4=Soufiane|last5=Wang|first5=Li|last6=Brisebarre|first6=Audrey|last7=Dubois|first7=Christine|last8=Nkusi|first8=Erwin|last9=Lenglez|first9=Sandrine|date=2017-02-02|title=Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition|url=http://www.cell.com/cell-stem-cell/abstract/S1934-5909(16)30359-9|journal=Cell Stem Cell|language=English|volume=20|issue=2|pages=191–204.e5|doi=10.1016/j.stem.2016.10.018|issn=1934-5909|pmid=27889319}} 12. ^{{Cite journal|last=Thomson|first=Sophie R.|last2=Seo|first2=Sang S.|last3=Barnes|first3=Stephanie A.|last4=Louros|first4=Susana R.|last5=Muscas|first5=Melania|last6=Dando|first6=Owen|last7=Kirby|first7=Caoimhe|last8=Wyllie|first8=David J. A.|last9=Hardingham|first9=Giles E.|date=2017-08-02|title=Cell-Type-Specific Translation Profiling Reveals a Novel Strategy for Treating Fragile X Syndrome|url=http://www.cell.com/neuron/abstract/S0896-6273(17)30635-9|journal=Neuron|language=English|volume=95|issue=3|pages=550–563.e5|doi=10.1016/j.neuron.2017.07.013|issn=0896-6273|pmid=28772121}} 13. ^{{Cite journal|last=Cooper|first=Aaron R.|last2=Lill|first2=Georgia R.|last3=Shaw|first3=Kit|last4=Carbonaro|first4=Denise|last5=Davila|first5=Alejandra|last6=Sokolic|first6=Robert|last7=Candotti|first7=Fabio|last8=Pellegrini|first8=Matteo|last9=Kohn|first9=Donald B.|date=2017-01-01|title=Cytoreductive conditioning intensity predicts clonal diversity in ADA-SCID retroviral gene therapy patients|url=http://www.bloodjournal.org/content/early/2017/03/28/blood-2016-12-756734|journal=Blood|language=en|pages=blood–2016–12-756734|doi=10.1182/blood-2016-12-756734|issn=0006-4971|pmid=28351939}} 14. ^{{Cite journal|last=Nikolić|first=Marko Z|last2=Caritg|first2=Oriol|last3=Jeng|first3=Quitz|last4=Johnson|first4=Jo-Anne|last5=Sun|first5=Dawei|last6=Howell|first6=Kate J|last7=Brady|first7=Jane L|last8=Laresgoiti|first8=Usua|last9=Allen|first9=George|title=Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids|journal=eLife|volume=6|doi=10.7554/eLife.26575|issn=2050-084X|pmc=5555721|pmid=28665271}} 15. ^{{Cite journal|last=Gong|first=Yu-Nong|last2=Chen|first2=Guang-Wu|last3=Yang|first3=Shu-Li|last4=Lee|first4=Ching-Ju|last5=Shih|first5=Shin-Ru|last6=Tsao|first6=Kuo-Chien|date=2016-03-17|title=A Next-Generation Sequencing Data Analysis Pipeline for Detecting Unknown Pathogens from Mixed Clinical Samples and Revealing Their Genetic Diversity|url=http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0151495|journal=PLOS ONE|volume=11|issue=3|pages=e0151495|doi=10.1371/journal.pone.0151495|issn=1932-6203}} 16. ^{{Cite journal|last=Heim|first=Joel B.|last2=Squirewell|first2=Edwin J.|last3=Neu|first3=Ancilla|last4=Zocher|first4=Georg|last5=Sominidi-Damodaran|first5=Sindhuja|last6=Wyles|first6=Saranya P.|last7=Nikolova|first7=Ekaterina|last8=Behrendt|first8=Nille|last9=Saunte|first9=Ditte M.|date=2017-04-11|title=Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix|url=http://www.pnas.org/content/114/15/3933|journal=Proceedings of the National Academy of Sciences|language=en|volume=114|issue=15|pages=3933–3938|doi=10.1073/pnas.1614894114|issn=0027-8424|pmid=28348210}} 17. ^{{cite web|url=http://iai.asm.org/content/78/3/1040.full|title=Cell Sorting-Assisted Microarray Profiling of Host Cell Response to Cryptosporidium parvum Infection|last1=Yang|first1=Yi-Lin|last2=Buck|first2=Gregory A.|date=1 March 2010|website=Infection and Immunity|pages=1040–1048|language=en|doi=10.1128/IAI.01009-09|accessdate=2 October 2017|last3=Widmer|first3=Giovanni}} 18. ^{{Cite news|url=http://www.clpmag.com/2017/10/cambridge-epigenetix-nugen-technologies-team-epigenetics-research/|title=Cambridge Epigenetix, NuGen Technologies Team Up for Epigenetics Research - Clinical Lab Products|work=Clinical Lab Products|access-date=2017-11-01|language=en-US}} 1 : Biotechnology companies of the United States |
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