| 词条 | Pipethiaden |
| 释义 |
| Verifiedfields = | verifiedrevid = | IUPAC_name = 1-Methyl-4-(thieno[2,3-c][2]benzothiepin-4(9H)-ylidene)piperidine | image = Pipethiaden.svg | width = 175 | CAS_number_Ref = | CAS_number = 15053-99-3 | ATC_prefix = None | ATC_suffix = | PubChem = 197209 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 170786 | UNII_Ref = | UNII = 4M164I6E36 | KEGG_Ref = | KEGG = | ChEMBL_Ref = | ChEMBL = | C=18 | H=19 | N=1 | S=2 | molecular_weight = 313.096 g/mol | smiles = CN1CCC(=C2c3ccccc3CSc4c2ccs4)CC1 | StdInChI_Ref = | StdInChI = InChI=1S/C18H19NS2/c1-19-9-6-13(7-10-19)17-15-5-3-2-4-14(15)12-21-18-16(17)8-11-20-18/h2-5,8,11H,6-7,9-10,12H2,1H3 | StdInChIKey_Ref = | StdInChIKey = VZWWTHTUQTYAGH-UHFFFAOYSA-N[1] }}Pipethiaden is a benzothiepin-based drug candidate that was at one time studied as a potential preventative to reduce the frequency of recurrent migraine headaches. It also has some activity as an antihistamine acting mainly at the 5-HT2A and 5HT2C receptors.[2] References1. ^{{cite web|url=http://www.chemspider.com/Chemical-Structure.170786.html|title=1-Methyl-4-(thieno[2,3-c][2]benzothiepin-4(9H)-ylidene)piperidine|publisher=}} {{Antimigraine preparations}}{{Pharma-stub}}2. ^{{cite journal | last1 = Frycová | first1 = H | last2 = Metys | first2 = J | title = Anti-allergic Properties of Pipethiaden—a New Preventive Agent for Migraine | journal = Československá Farmacie | date = July 1989 | volume = 38 | issue = 6 | pages = 264–8 | pmid = 2790993 | language = Czech}} 4 : Abandoned drugs|5-HT2 antagonists|H1 receptor antagonists|Piperidines |
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