| 词条 | Brian Morris (biologist) |
| 释义 |
| honorific_prefix = | name = Brian J. Morris | honorific_suffix = | native_name = | native_name_lang = | image = | image_size = | image_upright = | alt = | caption = | birth_date = {{birth date and age|1950|07|14}} | birth_place = Adelaide, Australia | death_date = | death_place = | death_cause = | resting_place = | resting_place_coordinates = | other_names = | pronounce = | residence = | citizenship = | nationality = Australian | fields = Molecular biology, molecular genetics | workplaces = University of Sydney | patrons = | education = | alma_mater = University of Adelaide, Monash University, University of Melbourne | thesis_title = The renin-angiotensin system in kidney cells | thesis_url = | thesis_year = 1975 | doctoral_advisor = | academic_advisors = | doctoral_students = | notable_students = | known_for = Work on hypertension and circumcision | influences = | influenced = | awards = Royal Society of New South Wales' Edgeworth David Medal (1985) | author_abbrev_bot = | author_abbrev_zoo = | spouse = | partner = | children = | signature = | signature_alt = | website = | footnotes = }} Brian James Morris (born 14 July 1950)[1] is a professor emeritus of molecular medical sciences at the University of Sydney, Australia. Education and appointmentsBrian Morris grew up in Adelaide, South Australia, where he graduated from the University of Adelaide in 1972. He then completed his PhD at Monash University and the University of Melbourne in 1975. From 1975–1978 he did postdoctoral research at the University of Missouri, and the University of California, San Francisco, first as a CJ Martin fellow, and then as an Advanced Fellow of the American Heart Association. He was then appointed as an academic at the University of Sydney in 1978, was appointed a professor in 1999, and was appointed Professor Emeritus in 2013.[2][3] He retired in 2014 and the Bosch Institute of Medical Research took over his lab space.[3]{{rp|18}} CareerMorris studied the Renin–angiotensin system (RAS) for most of his career. His interest in RAS began during his undergraduate studies, when he worked for a while in the laboratory where Eugenie Lumbers had just found early clues to the existence of prorenin (the protein precursor of renin) during her PhD work. He remained interested in the field, and had the good fortune to move to the University of California, San Francisco in the mid-1970s, a center for the development of the tools of biotechnology and molecular cloning. He joined others in applying those tools to RAS, and was among the pioneers is isolating the gene for renin itself, along with the prorenin and kallikrein genes, and the cardiac myosin heavy chain gene.[3][4] He and his team were among first to elucidate the biosynthetic pathway of renin, as well as key molecular mechanisms in renin's transcriptional and posttranscriptional control.[3] Taking that work further, he helped pioneer the field of genetic variation in hypertension.[5] Morris strongly supported male circumcision throughout his career, with around a quarter of his publications being on that topic, and joining the public debate.[2] He has likened those who oppose circumcision to anti-vaccine advocates.[6][7] He has criticised the circumcision policies of the Royal Australasian College of Physicians through the years.[8][9] In the 2000s, he began to study the genetics of longevity, including the roles of FOXO3 and the sirtuins.[3]{{rp|154-155}} Awards and honoursHe was awarded the Royal Society of New South Wales' Edgeworth David Medal in 1985 and in 1993 the University of Sydney awarded him a DSc. In 2003 he was elected as an Honorary Fellow of the American Heart Association Council for High Blood Pressure Research. In 2010 he gave the Lewis K. Dahl Memorial lecture, an award sponsored by the Council for High Blood Pressure Research in association with the American Heart Association. In 2014 the AHA awarded him the Irvine Page--Alva Bradley Lifetime Achievement Award. He was made a Member of the Order of Australia in the Queens Birthday Honours Awards in 2018.[2][5] References1. ^{{cite web |title=Morris, Brian J. (Brian James), 1950- |url=http://id.loc.gov/authorities/names/no2003112947.html |publisher=Library of Congress |accessdate=23 August 2018}} 2. ^1 2 {{cite web | url=http://sydney.edu.au/medicine/people/academics/profiles/brian.morris.php | title=Professor Emeritus Brian Morris | work=University of Sydney | accessdate=22 August 2018}} 3. ^1 {{cite book |title=Triennial Report 2013-2015 |date=3 November 2016 |publisher=Bosch Institute of Medical Research at University of Sydney |url=http://sydney.edu.au/medicine/bosch/documents/news/events/2017/Bosch_Triennial_Report_2013-2015.pdf|archiveurl=https://web.archive.org/web/20180823041235/http://sydney.edu.au/medicine/bosch/documents/news/events/2017/Bosch_Triennial_Report_2013-2015.pdf|archivedate=22 August 2018}} 4. ^{{cite web | url=http://www.smh.com.au/national/health/thriving-under-pressure-scientist-unlocks-mysteries-of-hypertension-20111030-1mqh6.html | title=Thriving under pressure: scientist unlocks mysteries of hypertension | work=The Sydney Morning Herald | date=31 October 2011 | accessdate=6 February 2015 | author=Metherell, Mark}} 5. ^1 2 3 4 {{cite journal|last1=Morris|first1=B. J.|title=2010 Dahl Lecture: Renin, Genes, and Beyond: 40 Years of Molecular Discoveries in the Hypertension Field|journal=Hypertension|date=10 January 2011|volume=57|issue=3|pages=538–548|doi=10.1161/HYPERTENSIONAHA.110.166967|pmid=21220705}} {{open access}} 6. ^{{cite journal|last1=Collier|first1=R.|title=Ugly, messy and nasty debate surrounds circumcision|journal=Canadian Medical Association Journal|date=28 November 2011|volume=184|issue=1|pages=E25–E26|doi=10.1503/cmaj.109-4017|pmid=22125336|pmc=3255195}} 7. ^{{cite news | url=http://www.thedailybeast.com/articles/2014/04/02/new-journal-argues-circumcisions-should-be-mandatory.html | title=New Study Says Benefits of Circumcision Outweigh Risks 100 to 1 | newspaper=The Daily Beast | date=2 April 2014 | accessdate=31 March 2015 | author=Zadrozny, Brandy}} 8. ^{{cite journal |last1=Morris |first1=BJ |last2=Bailis |first2=SA |last3=Castellsague |first3=X |last4=Wiswell |first4=TE |last5=Halperin |first5=DT |title=RACP's policy statement on infant male circumcision is ill-conceived. |journal=Australian and New Zealand Journal of Public Health |date=February 2006 |volume=30 |issue=1 |pages=16–22; discussion 22–5 |pmid=16502947|doi=10.1111/j.1467-842X.2006.tb00079.x }} 9. ^{{cite journal |last1=Morris |first1=BJ |last2=Wodak |first2=AD |last3=Mindel |first3=A |last4=Schrieber |first4=L |last5=Duggan |first5=KA |last6=Dilley |first6=A |last7=Willcourt |first7=RJ |last8=Lowy |first8=M |last9=Cooper |first9=DA |title=The 2010 Royal Australasian College of Physicians' policy statement 'Circumcision of infant males' is not evidence based. |journal=Internal Medicine Journal |date=July 2012 |volume=42 |issue=7 |pages=822–8 |doi=10.1111/j.1445-5994.2012.02823.x |pmid=22805686}} External links
11 : 1950 births|Australian academics|Australian biologists|Circumcision debate|Living people|Monash University alumni|Members of the Order of Australia|University of Adelaide alumni|University of Melbourne alumni|University of Missouri staff|University of Sydney faculty |
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