“Caffeoyl-CoA O-methyltransferase”的意思、由来-开放百科全书

词条

Caffeoyl-CoA O-methyltransferase

释义

Structural studies
References

{{enzyme
| Name = caffeoyl-CoA O-methyltransferase
| EC_number = 2.1.1.104
| CAS_number = 120433-42-3
| IUBMB_EC_number = 2/1/1/104
| GO_code = 0042409
| image =
| width =
| caption =
}}

In enzymology, a caffeoyl-CoA O-methyltransferase ({{EC number|2.1.1.104}}) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + caffeoyl-CoA S-adenosyl-L-homocysteine + feruloyl-CoA

Thus, the two substrates of this enzyme are S-adenosyl methionine and caffeoyl-CoA, whereas its two products are S-adenosylhomocysteine and feruloyl-CoA. A large number of natural products are generated via a step involving this enzyme.^[1]

This enzyme is classified to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase. Other names in common use include caffeoyl coenzyme A methyltransferase, caffeoyl-CoA 3-O-methyltransferase, and trans-caffeoyl-CoA 3-O-methyltransferase. This enzyme participates in phenylpropanoid biosynthesis.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes {{PDB link|1SUI}} and {{PDB link|1SUS}}.

References

1. ^Wout Boerjan, John Ralph, Marie Baucher "Lignin Biosynthesis" Annu. Rev. Plant Biol. 2003, vol. 54, pp. 519–46. {{doi|10.1146/annurev.arplant.54.031902.134938}}

3 : EC 2.1.1|Enzymes of known structure|O-Methylated hydroxycinnamic acids metabolism

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。