词条 | Colfosceril palmitate |
释义 |
| Verifiedfields = changed | verifiedrevid = 460106521 | IUPAC_name = 2,3-di(hexadecanoyloxy)propyl 2-trimethylazaniumylethyl phosphate | image = Colfosceril Palmitate.png | width = 300 | tradename = Exosurf | Drugs.com = {{drugs.com|international|colfosceril-palmitate}} | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 63-89-8 | ATC_prefix = R07 | ATC_suffix = AA01 | PubChem = 6138 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 5908 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 319X2NFW0A | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D03585 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 1200737 | C=40 | H=80 | N=1 | O=8 | P=1 | molecular_weight = 734.039 g/mol | smiles = O=C(OCC(OC(=O)CCCCCCCCCCCCCCC)COP([O-])(=O)OCC[N+](C)(C)C)CCCCCCCCCCCCCCC | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = KILNVBDSWZSGLL-UHFFFAOYSA-N | synonyms = [2-({[2,3-bis(hexadecanoyloxy)propyl] phosphonato}oxy)ethyl]trimethylazanium }} Colfosceril palmitate (trade name Exosurf) is a drug used as a pulmonary surfactant.[1] It is a drug that is used in surfactant deficient conditions such as infant respiratory distress syndrome in newborns. See also
References1. ^{{Cite journal | doi = 10.1089/jam.1996.9.123 | last1 = Rubin | first1 = B. K. | title = Therapeutic aerosols and airway secretions | journal = Journal of Aerosol Medicine | volume = 9 | issue = 1 | pages = 123–130 | year = 1996 | pmid = 10160202}} {{Other respiratory system products}}{{DEFAULTSORT:Colfosceril Palmitate}}{{respiratory-system-drug-stub}} 3 : Palmitates|Organophosphates|Fatty acid esters |
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