| 词条 | Craniotabes |
| 释义 |
| name = Craniotabes | synonyms = | image = Cranial bones en.svg | alt = | caption = Cranial bones | pronounce = | field = Pediatrics | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }}Craniotabes is softening or thinning of the skull in infants and children, which may be normally present in newborns. It is seen mostly in the occipital and parietal bones. The bones are soft, and when pressure is applied they will collapse underneath it. When the pressure is relieved, the bones will usually snap back into place.[1][2] CausesAny condition that affects bone growth, most notably rickets[3][4] (from vitamin D deficiency),[5] marasmus, syphilis, or thalassemia, can cause craniotabes if present during a time of rapid skull growth (most especially during gestation and infancy). It can be a "normal" feature in premature infants. It is the first sign in children and infants with rickets. DiagnosisPhysical examination Management{{Empty section|date=September 2017}}EtymologyThe term (cranio- + tabes) is derived from the Latin words cranium for skull and tabes for wasting. References1. ^{{cite journal|last1=Harvey|first1=Nicholas C.|last2=Holroyd|first2=Christopher|last3=Ntani|first3=Georgia|last4=Javaid|first4=Kassim|last5=Cooper|first5=Philip|last6=Moon|first6=Rebecca|last7=Cole|first7=Zoe|last8=Tinati|first8=Tannaze|last9=Godfrey|first9=Keith|last10=Dennison|first10=Elaine|last11=Bishop|first11=Nicholas J.|last12=Baird|first12=Janis|last13=Cooper|first13=Cyrus|title=Vitamin D supplementation in pregnancy: a systematic review|journal=Health Technology Assessment (Winchester, England)|date=2014|volume=18|issue=45|pages=1–190|doi=10.3310/hta18450|url=https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0081705/|issn=2046-4924}} 2. ^{{cite journal|last1=Prentice|first1=Ann|title=Nutritional rickets around the world|journal=The Journal of Steroid Biochemistry and Molecular Biology|date=July 2013|volume=136|pages=201–206|doi=10.1016/j.jsbmb.2012.11.018|pmid=23220549}} 3. ^{{cite journal|last1=Elidrissy|first1=Abdelwahab T. H.|title=The Return of Congenital Rickets, Are We Missing Occult Cases?|journal=Calcified Tissue International|date=31 May 2016|volume=99|issue=3|pages=227–236|doi=10.1007/s00223-016-0146-2|pmid=27245342}} 4. ^{{cite journal|last1=Paterson|first1=Colin R.|last2=Ayoub|first2=David|title=Congenital rickets due to vitamin D deficiency in the mothers|journal=Clinical Nutrition|date=October 2015|volume=34|issue=5|pages=793–798|doi=10.1016/j.clnu.2014.12.006|pmid=25552383}} 5. ^{{cite journal|last1=Ercan|first1=Makbule|title=Relationship between newborn craniotabes and vitamin D status|journal=Northern Clinics of Istanbul|date=2016|doi=10.14744/nci.2016.48403|pmid=28058380|pmc=5175072}} External links{{Medical resources| DiseasesDB = | ICD10 = | ICD9 = | ICDO = | OMIM = | MedlinePlus = 001591 | eMedicineSubj = | eMedicineTopic = | MeSH = | GeneReviewsNBK = | GeneReviewsName = }}{{musculoskeletal-disease-stub}} 1 : Pediatrics |
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