“Cyclohexanol dehydrogenase”的意思、由来-开放百科全书

词条

Cyclohexanol dehydrogenase

释义

References

{{enzyme
| Name = cyclohexanol dehydrogenase
| EC_number = 1.1.1.245
| CAS_number = 63951-98-4
| IUBMB_EC_number = 1/1/1/245
| GO_code = 0018460
| image =
| width =
| caption =
}}

In enzymology, a cyclohexanol dehydrogenase ({{EC number|1.1.1.245}}) is an enzyme that catalyzes the chemical reaction

cyclohexanol + NAD⁺ cyclohexanone + NADH + H⁺

Thus, the two substrates of this enzyme are cyclohexanol and NAD⁺, whereas its 3 products are cyclohexanone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is cyclohexanol:NAD⁺ oxidoreductase. This enzyme participates in caprolactam degradation.

References

{{cite journal | vauthors = Dangel W, Tschech A, Fuchs G | last-author-amp = yes | year = 1989 | title = Enzyme-reactions involved in anaerobic cyclohexanol metabolism by a denitrifying Pseudomonas species | journal = Arch. Microbiol. | volume = 152 | pages = 273–279 | doi = 10.1007/BF00409663 | pmid=2505723 | issue = 3}}
{{cite journal | vauthors = Donoghue NA, Trudgill PW | year = 1975 | title = The metabolism of cyclohexanol by Acinetobacter NCIB 9871 | journal = Eur. J. Biochem. | volume = 60 | pages = 1–7 | pmid = 1261 | doi = 10.1111/j.1432-1033.1975.tb20968.x | issue = 1 }}
{{cite journal | vauthors = Trower MK, Buckland RM, Higgins R, Griffin M | year = 1985 | title = Isolation and Characterization of a Cyclohexane-Metabolizing Xanthobacter sp | journal = Appl. Environ. Microbiol. | volume = 49 | pages = 1282–1289 | pmid = 16346796 | issue = 5 | pmc = 238543 }}

3 : EC 1.1.1|NADH-dependent enzymes|Enzymes of unknown structure

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