| 词条 | Deborah Doniach |
| 释义 |
Life and workDoniach was educated at the Lycée Molière, Paris, began her medical studies at the Sorbonne and completed them at Royal Free Medical School, London.[1][2] She was employed as a research assistant at the Royal Free Hospital then as an endocrinologist at Middlesex Hospital, London where she worked with the eminent thyroid surgeon, Rupert Vaughan-Hudson.[1][5] Her observation of patients with Hashimoto's disease and knowledge of the field led her to realise that excess antibodies were an autoimmune reaction against the thyroid gland itself rather than external microbes.[1][2] She collaborated with Ivan Roitt and Peter Campbell to further understand the autoimmune basis of Hashimoto's disease (citations). Doniach continued her studies at Middlesex Hospital with various collaborators, including Roitt, Sheila Sherlock, Keith Taylor, and Gianfranco Bottazzo, and uncovered an autoimmune basis for numerous diseases, including pernicious anemia, primary biliary cirrhosis, and type I diabetes [1][2] This led to the concept of organ-specific auto-immunity.[5] In the 1960s she joined the then-new Department of Immunology at Middlesex where she was appointed as one of the first Consultant Immunopathologists. In 1974 she became Professor of Clinical Immunology.[2][5] Doniach is the mother of Sebastian Doniach, a condensed matter physicist at Stanford University. Selected Awards
Selected Published Works
References1. ^1 2 3 4 {{cite web|title=European Thyroid Association - Milestones - Deborah Doniach (1912-2004)|url=http://www.eurothyroid.com/about/met/doniach.html|work=European Thyroid Association|accessdate=1 November 2012}} {{Authority control}}{{DEFAULTSORT:Doniach, Deborah}}2. ^1 2 3 4 5 {{cite news|last=Brostoff|first=Jonathan|title=Obituary: Deborah Doniach|url=https://www.theguardian.com/society/2004/jan/15/health.obituaries|work=The Guardian Newspaper|publisher=The Guardian Newspaper|accessdate=1 November 2012|location=London|date=15 January 2004}} 3. ^1 2 3 4 {{cite journal|last=Wright|first=Pearce|title=Deborah Doniach|journal=The Lancet|date=20 March 2004|volume=363|issue=9413|pages=995|doi=10.1016/S0140-6736(04)15809-1|url=http://www.lancet.com/journals/lancet/article/PIIS0140-6736%2804%2915809-1/fulltext|accessdate=1 November 2012}} 15 : 1912 births|2004 deaths|20th-century British medical doctors|21st-century British medical doctors|British immunologists|British women medical doctors|People from Geneva|People from London|Swiss women physicians|20th-century Swiss physicians|21st-century Swiss physicians|Alumni of the UCL Medical School|20th-century women physicians|21st-century women physicians|20th-century women scientists |
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