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词条 4-HO-DET
释义

  1. Analogs

  2. History

  3. Dosage

  4. Effects

  5. Drug prohibition laws

     Sweden 

  6. See also

  7. References

  8. External links

{{refimprove|date=June 2013}}{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 477221917
| IUPAC_name = 3-(2-Diethylaminoethyl)-1H-indol-4-ol
| image = 4-HO-DET.svg
| width = 140
| image2 = 4-HO-DET-3d-sticks.png
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK = Class A
| legal_US =
| legal_DE = Anlage I
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 22204-89-3
| ATC_prefix =
| ATC_suffix =
| PubChem = 9991554
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 8167136
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 143202
| C=14 | H=20 | N=2 | O=1
| smiles = CCN(CC)CCc1c[nH]c2cccc(O)c12
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C14H20N2O/c1-3-16(4-2)9-8-11-10-15-12-6-5-7-13(17)14(11)12/h5-7,10,15,17H,3-4,8-9H2,1-2H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = OHHYMKDBKJPILO-UHFFFAOYSA-N
| melting_point = 104
| melting_high = 106
}}

4-HO-DET, also known as 4-hydroxy-diethyl-tryptamine, CZ-74, is a hallucinogenic drug and psychedelic compound of moderate duration. 4-HO-DET is a substituted tryptamine, structurally related to psilocin, ethocybin, and 4-HO-DIPT.

Analogs

The acetic acid ester of 4-HO-DET is known as 4-AcO-DET. The phosphoric acid ester of 4-HO-DET is known as 4-phosphoryloxy-DET, CEY-19, or ethocybin.

History

4-HO-DET received the lab code CZ-74 in the late 1950s by the inventors of the substance, Albert Hofmann and Franz Troxler. The substance was used together with its phosphoryloxy-analog ethocybin in human clinical trials in the 1960s by the German researchers Hanscarl Leuner and G. Baer.{{cn|date=June 2017}}

Dosage

10-25 mg is the usual oral dosage for 4-HO-DET, while the acetate and phosphate esters are said to require a slightly higher dosage.{{cn|date=June 2017}}

Effects

4-HO-DET produces entheogenic effects similar to LSD and psilocybin.{{medcn|date=June 2017}}

Drug prohibition laws

Sweden

Sveriges riksdags health ministry Statens folkhälsoinstitut classified 4-HO-DET as "health hazard" under the act Lagen om förbud mot vissa hälsofarliga varor (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of Nov 1, 2005, in their regulation SFS 2005:733 listed as 4-hydroxi-N,N-diethyltryptamin (4-HO-DET), making it illegal to sell or possess.[1]

See also

  • TiHKAL
  • Indoles

References

1. ^http://www.notisum.se/rnp/sls/sfs/20050733.pdf

External links

  • TiHKAL 4-HO-DET information at Erowid
  • 4-HO-DET entry in TiHKAL • info
  • Ethacetin degradation
{{Hallucinogens}}{{TiHKAL}}{{Tryptamines}}

3 : Phenols|Psychedelic tryptamines|Designer drugs

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