释义 |
- Interactions
- References
- Further reading
- External links
{{Infobox_gene}}Heat shock protein beta-8 is a protein that in humans is encoded by the HSPB8 gene.[1][2][3] Interactions HSPB8 has been shown to interact with: - HSPB2,[4][4] and
- Hsp27.[5][6]
References1. ^{{cite journal | vauthors = Smith CC, Yu YX, Kulka M, Aurelian L | title = A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells | journal = J Biol Chem | volume = 275 | issue = 33 | pages = 25690–9 | date = Sep 2000 | pmid = 10833516 | pmc = | doi = 10.1074/jbc.M002140200 }} 2. ^{{cite journal | vauthors = Charpentier AH, Bednarek AK, Daniel RL, Hawkins KA, Laflin KJ, Gaddis S, MacLeod MC, Aldaz CM | title = Effects of estrogen on global gene expression: identification of novel targets of estrogen action | journal = Cancer Res | volume = 60 | issue = 21 | pages = 5977–83 | date = Nov 2000 | pmid = 11085516 | pmc = | doi = }} 3. ^{{cite web | title = Entrez Gene: HSPB8 Heat shock 22kDa protein 8| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26353| accessdate = }} 4. ^{{cite journal | vauthors = Benndorf R, Sun X, Gilmont RR, Biederman KJ, Molloy MP, Goodmurphy CW, Cheng H, Andrews PC, Welsh MJ | title = HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27) | journal = J. Biol. Chem. | volume = 276 | issue = 29 | pages = 26753–61 | date = Jul 2001 | pmid = 11342557 | doi = 10.1074/jbc.M103001200 }} 5. ^1 {{cite journal | vauthors = Sun X, Fontaine JM, Rest JS, Shelden EA, Welsh MJ, Benndorf R | title = Interaction of human HSP22 (HSPB8) with other small heat shock proteins | journal = J. Biol. Chem. | volume = 279 | issue = 4 | pages = 2394–402 | date = Jan 2004 | pmid = 14594798 | doi = 10.1074/jbc.M311324200 }} 6. ^{{cite journal | vauthors = Irobi J, Van Impe K, Seeman P, Jordanova A, Dierick I, Verpoorten N, Michalik A, De Vriendt E, Jacobs A, Van Gerwen V, Vennekens K, Mazanec R, Tournev I, Hilton-Jones D, Talbot K, Kremensky I, Van Den Bosch L, Robberecht W, Van Vandekerckhove J, Van Broeckhoven C, Gettemans J, De Jonghe P, Timmerman V | title = Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy | journal = Nat. Genet. | volume = 36 | issue = 6 | pages = 597–601 | date = Jun 2004 | pmid = 15122253 | doi = 10.1038/ng1328 }}
{{Clear}}Further reading{{refbegin | 2}}- {{cite journal | vauthors = Hu Z, Chen L, Zhang J, Li T, Tang J, Xu N, Wang X | title = Structure, function, property, and role in neurologic diseases and other diseases of the sHsp22 | journal = J. Neurosci. Res. | volume = 85 | issue = 10 | pages = 2071–9 | year = 2007 | pmid = 17304582 | doi = 10.1002/jnr.21231 }}
- {{cite journal | vauthors = Timmerman V, Raeymaekers P, Nelis E, De Jonghe P, Muylle L, Ceuterick C, Martin JJ, Van Broeckhoven C | title = Linkage analysis of distal hereditary motor neuropathy type II (distal HMN II) in a single pedigree | journal = J. Neurol. Sci. | volume = 109 | issue = 1 | pages = 41–8 | year = 1992 | pmid = 1517763 | doi = 10.1016/0022-510X(92)90091-X }}
- {{cite journal | vauthors = Berciano J, Combarros O, Figols J, Calleja J, Cabello A, Silos I, Coria F | title = Hereditary motor and sensory neuropathy type II. Clinicopathological study of a family | journal = Brain | volume = 109 ( Pt 5) | issue = 5 | pages = 897–914 | year = 1986 | pmid = 3022865 | doi = 10.1093/brain/109.5.897 }}
- {{cite journal | vauthors = Jansen PH, Joosten EM, Jaspar HH, Vingerhoets HM | title = A rapidly progressive autosomal dominant scapulohumeral form of spinal muscular atrophy | journal = Ann. Neurol. | volume = 20 | issue = 4 | pages = 538–40 | year = 1986 | pmid = 3789668 | doi = 10.1002/ana.410200417 }}
- {{cite journal | vauthors = Meadows JC, Marsden CD | title = A distal form of chronic spinal muscular atrophy | journal = Neurology | volume = 19 | issue = 1 | pages = 53–8 | year = 1969 | pmid = 5813127 | doi = 10.1212/wnl.19.1.53 }}
- {{cite journal | vauthors = D'Alessandro R, Montagna P, Govoni E, Pazzaglia P | title = Benign familial spinal muscular atrophy with hypertrophy of the calves | journal = Arch. Neurol. | volume = 39 | issue = 10 | pages = 657–60 | year = 1982 | pmid = 7125978 | doi = 10.1001/archneur.1982.00510220055013 }}
- {{cite journal | vauthors = Groen RJ, Sie OG, van Weerden TW | title = Dominant inherited distal spinal muscular atrophy with atrophic and hypertrophic calves | journal = J. Neurol. Sci. | volume = 114 | issue = 1 | pages = 81–4 | year = 1993 | pmid = 8433103 | doi = 10.1016/0022-510X(93)90053-2 }}
- {{cite journal | vauthors = Timmerman V, De Jonghe P, Simokovic S, Löfgren A, Beuten J, Nelis E, Ceuterick C, Martin JJ, Van Broeckhoven C | title = Distal hereditary motor neuropathy type II (distal HMN II): mapping of a locus to chromosome 12q24 | journal = Hum. Mol. Genet. | volume = 5 | issue = 7 | pages = 1065–9 | year = 1997 | pmid = 8817349 | doi = 10.1093/hmg/5.7.1065 }}
- {{cite journal | vauthors = Irobi J, Tissir F, De Jonghe P, De Vriendt E, Van Broeckhoven C, Timmerman V, Beuten J | title = A clone contig of 12q24.3 encompassing the distal hereditary motor neuropathy type II gene | journal = Genomics | volume = 65 | issue = 1 | pages = 34–43 | year = 2000 | pmid = 10777663 | doi = 10.1006/geno.2000.6149 }}
- {{cite journal | vauthors = Aurelian L, Smith CC, Winchurch R, Kulka M, Gyotoku T, Zaccaro L, Chrest FJ, Burnett JW | title = A novel gene expressed in human keratinocytes with long-term in vitro growth potential is required for cell growth | journal = J. Invest. Dermatol. | volume = 116 | issue = 2 | pages = 286–95 | year = 2001 | pmid = 11180006 | doi = 10.1046/j.1523-1747.2001.00191.x }}
- {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs | journal = Genome Res. | volume = 11 | issue = 3 | pages = 422–35 | year = 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}
- {{cite journal | vauthors = Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S | title = Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing | journal = EMBO Rep. | volume = 1 | issue = 3 | pages = 287–92 | year = 2001 | pmid = 11256614 | pmc = 1083732 | doi = 10.1093/embo-reports/kvd058 }}
- {{cite journal | vauthors = Yu YX, Heller A, Liehr T, Smith CC, Aurelian L | title = Expression analysis and chromosome location of a novel gene (H11) associated with the growth of human melanoma cells | journal = Int. J. Oncol. | volume = 18 | issue = 5 | pages = 905–11 | year = 2001 | pmid = 11295034 | doi = 10.3892/ijo.18.5.905 }}
- {{cite journal | vauthors = Benndorf R, Sun X, Gilmont RR, Biederman KJ, Molloy MP, Goodmurphy CW, Cheng H, Andrews PC, Welsh MJ | title = HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27) | journal = J. Biol. Chem. | volume = 276 | issue = 29 | pages = 26753–61 | year = 2001 | pmid = 11342557 | doi = 10.1074/jbc.M103001200 }}
- {{cite journal | vauthors = Kappé G, Verschuure P, Philipsen RL, Staalduinen AA, Van de Boogaart P, Boelens WC, De Jong WW | title = Characterization of two novel human small heat shock proteins: protein kinase-related HspB8 and testis-specific HspB9 | journal = Biochim. Biophys. Acta | volume = 1520 | issue = 1 | pages = 1–6 | year = 2001 | pmid = 11470154 | doi = 10.1016/s0167-4781(01)00237-8 }}
- {{cite journal | vauthors = Suzuki H, Fukunishi Y, Kagawa I, Saito R, Oda H, Endo T, Kondo S, Bono H, Okazaki Y, Hayashizaki Y | title = Protein–Protein Interaction Panel Using Mouse Full-Length cDNAs | journal = Genome Res. | volume = 11 | issue = 10 | pages = 1758–65 | year = 2001 | pmid = 11591653 | pmc = 311163 | doi = 10.1101/gr.180101 }}
- {{cite journal | vauthors = Molloy MP, Andrews PC | title = Phosphopeptide derivatization signatures to identify serine and threonine phosphorylated peptides by mass spectrometry | journal = Anal. Chem. | volume = 73 | issue = 22 | pages = 5387–94 | year = 2002 | pmid = 11816564 | doi = 10.1021/ac0104227 }}
- {{cite journal | vauthors = Depre C, Hase M, Gaussin V, Zajac A, Wang L, Hittinger L, Ghaleh B, Yu X, Kudej RK, Wagner T, Sadoshima J, Vatner SF | title = H11 kinase is a novel mediator of myocardial hypertrophy in vivo | journal = Circ. Res. | volume = 91 | issue = 11 | pages = 1007–14 | year = 2002 | pmid = 12456486 | doi = 10.1161/01.RES.0000044380.54893.4B }}
{{refend}}External links- [https://www.ncbi.nlm.nih.gov/books/NBK1285/ GeneReviews/NCBI/NIH/UW entry on Charcot-Marie-Tooth Neuropathy Type 2]
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