JRB may refer to:

• ISO 639-3 code (jrb) for Judeo-Arabic language
• Jatiya Rakkhi Bahini - Bangladeshi para-military force
• The Downtown Manhattan Heliport, IATA/FAA Airport code JRB or KJRB
• Janice Rogers Brown (Born 1949), United States Court of Appeals DC circuit judge, 2003-present
• Jason Robert Brown - Musical theatre composer
• John Ross Bowie, an American actor
• Vice-President Joseph Robinette Biden, Jr.
• Judge Roy Bean
• Juggalo Rydas Bitch, a midwestern street gang.
• James River Bridge, the James River Bridge in Newport News, Virginia.
• Jean-Robert Bellande

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