KRSC may refer to:

• KRSC (AM), a radio station (1400 AM) licensed to serve Othello, Washington, United States
• KRSC-FM, a radio station (91.3 FM) licensed to serve Claremore, Oklahoma, United States
• KKNW, a radio station (1150 AM) licensed to serve Seattle, Washington, which held the call sign KRSC from 1927 to 1949
• KING-FM, a radio station (98.1 FM) licensed to serve Seattle, Washington, which held the call sign KRSC-FM from 1947 to 1958
• KRSU-TV, a television station (channel 36/PSIP 35) licensed to serve Claremore, Oklahoma, which held the call sign KRSC-TV from 1992 to 2013

• 501(c)3
• 501(c)(3)
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• 501(c)(6)
• 501(c) organization
• 501 Queen
• 501st Legion
• 501 Urhixidur
• 502
• 5020 Asimov
• 502 BC
• 502 BCE
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• 503
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• 503rd Infantry Regiment (United States)
• 504
• 5040 (number)
• 504 BC
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• 504 King
• 504 (record label)