| 词条 | Cuscohygrine |
| 释义 |
| Name = Cuscohygrine | IUPACName = 1-[(2R)-1-Methyl-2-pyrrolidinyl]-3-[(2S)-1-methyl-2-pyrrolidinyl]acetone | ImageFile = Cuscohygrine.svg | ImageSize = 200px | ImageName = Chemical structure of cuscohygrine | ImageFile2 = Cuscohygrine ball-and-stick.png | Section1 = {{Chembox Identifiers | ChemSpiderID = 21864896 | InChI=1S/C13H24N2O/c1-14-7-3-5-11(14)9-13(16)10-12-6-4-8-15(12)2/h11-12H,3-10H2,1-2H3/t11-,12+ | InChIKey = ZEBIACKKLGVLFZ-TXEJJXNPSA-N | CASNo = 454-14-8 | KEGG = C06521 | PubChem = 441070 | UNII = 93FJ3823VL | 3DMet = B05209 | SMILES = CN1CCC[C@@H]1CC(=O)C[C@@H]2CCCN2C }} | Section2 = {{Chembox Properties | C=13 | H=24 | N=2 | O=1 | MeltingPtC = 40-41 | MeltingPt_notes = (trihydrate) | BoilingPt = | Density = }} }} Cuscohygrine is a pyrrolidine alkaloid found in coca. It can also be extracted from plants of the family Solanaceae, including Atropa belladonna (deadly nightshade), Datura innoxia and Datura stramonium (jimson weed). Cuscohygrine usually occurs along with other, more potent alkaloids such as atropine or cocaine. Cuscohygrine, along with the related metabolite hygrine, was first isolated by Carl Liebermann in 1889 as an alkaloid accompanying cocaine in coca leaves (also known as Cusco-leaves). Cuscohygrine is an oil that can be distilled without decomposition only in vacuum. It is soluble in water. It also forms a crystalline trihydrate which melts at 40–41 °C. See also
References
4 : Pyrrolidine alkaloids|Alkaloids found in Erythroxylum coca|Alkaloids found in Solanaceae|Ketones |
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