| 词条 | Lisinopril/hydrochlorothiazide |
| 释义 |
| verifiedrevid = 447439314 | type = combo | component1 = Lisinopril | class1 = ACE inhibitor | component2 = Hydrochlorothiazide | class2 = Thiazide diuretic | Drugs.com = {{drugs.com|mtm|hydrochlorothiazide-and-lisinopril}} | tradename = Zestoretic, Prinzide, others | MedlinePlus = a601070 | pregnancy_AU = | pregnancy_US = D | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = Rx-only | routes_of_administration = By mouth | ATC_prefix = C09 | ATC_suffix = BA03 }}Lisinopril/hydrochlorothiazide, sold under the trade name Zestoretic among others, is a combination of the medications lisinopril, an ACE inhibitor, and hydrochlorothiazide, a diuretic.[1] It is used to treat high blood pressure.[1] Typically it becomes an option once a person is doing well on the individual components.[3] It is taken by mouth.[1] Common side effects include dizziness, headache, cough, and feeling tired.[5] Severe side effects may include angioedema and low blood pressure.[5] Use during pregnancy may harm the baby.[1] The combination was approved for medical use in the United States in 1989.[2] It is available as a generic medication.[3] In the United States the wholesale cost per dose is less than 0.05 USD as of 2018.[4] In the United Kingdom it costs the NHS about 0.40 pounds per dose as of 2017.[3] In 2016 it was the 53rd most prescribed medication in the United States with more than 14 million prescriptions.[5] References1. ^1 2 {{cite web |title=Lisinopril and Hydrochlorothiazide - FDA prescribing information, side effects and uses |url=https://www.drugs.com/pro/lisinopril-and-hydrochlorothiazide.html |website=Drugs.com |publisher=Solco Healthcare LLC |language=en}} 2. ^1 2 3 {{cite web |title=Hydrochlorothiazide and lisinopril Uses, Side Effects & Warnings |url=https://www.drugs.com/mtm/hydrochlorothiazide-and-lisinopril.html |website=Drugs.com |publisher=Cerner Multum |accessdate=26 December 2018 |language=en}} 3. ^1 2 {{cite book|title=British national formulary : BNF 74|date=2017|publisher=British Medical Association|isbn=978-0857112989|page=166|edition=74}} 4. ^{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}} 5. ^{{cite web |title=The Top 300 of 2019 |url=https://clincalc.com/DrugStats/Top300Drugs.aspx |website=clincalc.com |accessdate=22 December 2018}} Further reading
3 : Antihypertensive agents|Combination drugs|RTT |
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