“N-sulfoglucosamine sulfohydrolase”的意思、由来-开放百科全书

词条

N-sulfoglucosamine sulfohydrolase

释义

References

{{enzyme
| Name = N-sulfoglucosamine sulfohydrolase
| EC_number = 3.10.1.1
| CAS_number = 37289-41-1
| IUBMB_EC_number = 3/10/1/1
| GO_code = 0016250
| image =
| width =
| caption =
}}

In enzymology, a N-sulfoglucosamine sulfohydrolase ({{EC number|3.10.1.1}}) is an enzyme that catalyzes the chemical reaction

N-sulfo-D-glucosamine + H₂O D-glucosamine + sulfate

Thus, the two substrates of this enzyme are N-sulfo-D-glucosamine and H₂O, whereas its two products are D-glucosamine and sulfate.

This enzyme belongs to the family of hydrolases, specifically those acting on sulfur-nitrogen bonds. The systematic name of this enzyme class is N-sulfo-D-glucosamine sulfohydrolase. Other names in common use include sulfoglucosamine sulfamidase, heparin sulfamidase, 2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate, and sulphohydrolase). This enzyme participates in glycosaminoglycan degradation and glycan structures - degradation.

This enzyme can also be found at SGSH

References

{{cite journal | author = Dietrich CP | date = 1969 | title = Enzymic degradation of heparin A sulphamidase and a sulphoesterase from Flavobacterium heparinum | journal = Biochem. J. | volume = 111 | pages = 91–5 | pmid = 5775690 | issue = 1 | pmc = 1187498 }}
{{cite journal | vauthors = Mahuran D, Clements P, Hopwood J | date = 1983 | title = A rapid four column purification of 2-deoxy-D-glucoside-2-sulphamate sulphohydrolase from human liver | journal = Biochim. Biophys. Acta | volume = 757 | pages = 359–65 | pmid = 6849981 | issue = 3 | doi=10.1016/0304-4165(83)90062-4}}

2 : EC 3.10.1|Enzymes of unknown structure

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