| 词条 | Pirisudanol |
| 释义 |
| verifiedrevid = 447813921 | IUPAC_name = 2-(dimethylamino)ethyl[5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridinyl]methylbutanedioate | image = Pirisudanol.png | tradename = | Drugs.com = {{drugs.com|international|pirisudanol}} | pregnancy_category = | legal_status = Rx-only | routes_of_administration = Oral | bioavailability = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 33605-94-6 | ATC_prefix = N06 | ATC_suffix = BX08 | PubChem = 65782 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = W618Z2SMVL | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D07347 | ChemSpiderID = 59202 | C=16 | H=24 | N=2 | O=6 | molecular_weight = 340.372 g/mol | smiles = CC1=NC=C(C(=C1O)CO)COC(=O)CCC(=O)OCCN(C)C | StdInChI = 1S/C16H24N2O6/c1-11-16(22)13(9-19)12(8-17-11)10-24-15(21)5-4-14(20)23-7-6-18(2)3/h8,19,22H,4-7,9-10H2,1-3H3 | StdInChIKey = KTOAWCPDBUCJED-UHFFFAOYSA-N }}Pirisudanol (Mentis, Menthen, Mentium, Nadex, Nadexen, Nadexon, Pridana, Stivane), also known as pyrisuccideanol, is the succinic acid ester of pyridoxine (a form of vitamin B6) and of deanol (DMAE).[1] It has been used in Europe in the treatment of mild cognitive impairment as well as fatigue and depression.[1][2][3][4][5] See also
References1. ^1 {{cite web | url = +http://www.dr-bob.org/cgi-bin/pb/mget.pl?post=/babble/20010708/msgs/69493.html#69493 | title = Psycho-Babble Medication Thread 69493 | format = | work = | accessdate = }} {{Nootropics}}{{Antidepressants}}{{Acetylcholine receptor modulators}}{{nervous-system-drug-stub}}2. ^{{cite book | author = David J. Triggle | title = Dictionary of Pharmacological Agents | publisher = Chapman & Hall/CRC | location = Boca Raton | year = 1996 | pages = | isbn = 0-412-46630-9 | oclc = | doi = | url = https://books.google.com/books?id=A0THacd46ZsC&lpg=PA1626&dq=Pirisudanol&as_brr=3&pg=PA1626#v=onepage&q=&f=false}} 3. ^{{cite journal |vauthors=Bathien N, Willer JC, Hugelin A | title = [Effect of psychotropic drugs on physiological variations and psychometric scores during attention] | language = French | journal = L'Encéphale | volume = 2 | issue = 1 | pages = 55–60 | year = 1976 | pmid = 1261486 | doi = | url = }} 4. ^{{cite journal | author = Murphy JE | title = An evaluation of pyrisuccideanol maleate (Nadex) in the treatment of mild to moderate depression in patients aged 55 years and over, presenting in general practice | journal = The Journal of International Medical Research | volume = 9 | issue = 5 | pages = 330–7 | year = 1981 | pmid = 7297757 | doi = | url = }} 5. ^{{cite journal | author = Zmorski T | title = [Experience with Nadex in an ambulatory psychiatric practice] | language = German | journal = Therapeutische Umschau. Revue Thérapeutique | volume = 40 | issue = 9 | pages = 817–20 |date=September 1983 | pmid = 6138876 | doi = | url = }} 8 : Cholinergics|Pyridines|Phenols|Alcohols|Succinates|Prodrugs|Nootropics|Antidepressants |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。