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词条 Prokineticin receptor
释义

  1. References

  2. External links

{{infobox protein
| Name = prokineticin receptor 1
| caption =
| image =
| width =
| HGNCid = 4524
| Symbol = PROKR1
| AltSymbols = GPR73
| EntrezGene = 10887
| OMIM = 607122
| RefSeq = NM_138964
| UniProt = Q8TCW9
| PDB =
| ECnumber =
| Chromosome = 2
| Arm = p
| Band = 14
| LocusSupplementaryData =
}}{{infobox protein
| Name = prokineticin receptor 2
| caption =
| image =
| width =
| HGNCid = 15836
| Symbol = PROKR2
| AltSymbols = GPR73L1
| EntrezGene = 128674
| OMIM = 607123
| RefSeq = NM_144773
| UniProt = Q8NFJ6
| PDB =
| ECnumber =
| Chromosome = 20
| Arm = p
| Band = 12.3
| LocusSupplementaryData =
}}

The prokineticin receptor is a G protein-coupled receptor which binds the peptide hormone prokineticin. There are two variants each encoded by a different gene (PROKR1, PROKR2).[1] These receptors mediate gastrointestinal smooth muscle contraction and angiogenesis.

References

1. ^{{cite journal |vauthors=Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY | title = Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor | journal = J. Biol. Chem. | volume = 277 | issue = 22 | pages = 19276–80 | year = 2002 | pmid = 11886876 | doi = 10.1074/jbc.M202139200 }}

External links

  • {{cite web | url = http://www.iuphar-db.org/GPCR/ChapterMenuForward?chapterID=1349 | title = Prokineticin Receptors | accessdate = | date = | format = | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | pages = | language = | archiveurl = | archivedate = | quote = }}
  • {{MeshName|PROKR1+protein,+human}}
  • {{MeshName|PROKR2+protein,+human}}
{{G protein-coupled receptors}}{{transmembranereceptor-stub}}

1 : G protein-coupled receptors

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