词条 | Prokineticin receptor |
释义 |
| Name = prokineticin receptor 1 | caption = | image = | width = | HGNCid = 4524 | Symbol = PROKR1 | AltSymbols = GPR73 | EntrezGene = 10887 | OMIM = 607122 | RefSeq = NM_138964 | UniProt = Q8TCW9 | PDB = | ECnumber = | Chromosome = 2 | Arm = p | Band = 14 | LocusSupplementaryData = }}{{infobox protein | Name = prokineticin receptor 2 | caption = | image = | width = | HGNCid = 15836 | Symbol = PROKR2 | AltSymbols = GPR73L1 | EntrezGene = 128674 | OMIM = 607123 | RefSeq = NM_144773 | UniProt = Q8NFJ6 | PDB = | ECnumber = | Chromosome = 20 | Arm = p | Band = 12.3 | LocusSupplementaryData = }} The prokineticin receptor is a G protein-coupled receptor which binds the peptide hormone prokineticin. There are two variants each encoded by a different gene (PROKR1, PROKR2).[1] These receptors mediate gastrointestinal smooth muscle contraction and angiogenesis. References1. ^{{cite journal |vauthors=Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY | title = Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor | journal = J. Biol. Chem. | volume = 277 | issue = 22 | pages = 19276–80 | year = 2002 | pmid = 11886876 | doi = 10.1074/jbc.M202139200 }} External links
1 : G protein-coupled receptors |
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