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词条 Actinomyces naeslundii
释义

  1. Description

  2. Role in disease

  3. References

  4. External links

{{short description|Species of bacterium}}{{Italic title}}{{Taxobox
| color = lightgrey
| name = Actinomyces naeslundii or Actinomyces oris
| image = Actinomyces naeslundii 01.jpg
| image_width = 240px
| image_caption = Histopathological changes due to A. naeslundii.
| regnum = Bacteria
| phylum = Actinobacteria
| ordo = Actinomycetales
| familia = Actinomycetaceae
| genus = Actinomyces
| species = A. naeslundii
| binomial = Actinomyces naeslundii
| binomial_authority = Thompson & Lovestedt 1951
}}Actinomyces naeslundii is a Gram-positive, rod-shaped bacterium found in the mouth of humans. The species has been implicated in periodontal disease, as well as various tooth cavities.[1] In other cases, A. naeslundii is associated with good oral health. It is one of the first bacteria to occupy the oral cavity and colonize the tooth's surface. It has also been isolated from women with bacterial vaginosis.[1]

Description

A. naeslundii appears Gram-positive and pleomorphic by microscopy. It does not form spores, and is considered anaerobic or microaerophilic.[3]

In 2009, the species A. naeslundi was split. Bacteria formerly known as "Actinomyces naeslundi genospecies 2" were reclassified under the new species name Actinomyces oris. Those formerly known as "Actinomyces naeslundi genospecies WVA 963" were reclassified as Actinomyces johnsonii.[2]

Role in disease

Many species of the genus Actinomyces, including A. naeslundii, cause a chronic disease called actinomycosis, which is characterized by swelling and formation of an abscess which may exude pus. This can be accompanied by tissue fibrosis.[3]

Infections of the mouth, face, and neck are the most commonly recognized infections; however, the thoracic region, abdomen, pelvis, and the central nervous system can also be involved.[4]

References

1. ^{{cite journal|last1=Africa|first1=Charlene|last2=Nel|first2=Janske|last3=Stemmet|first3=Megan|title=Anaerobes and Bacterial Vaginosis in Pregnancy: Virulence Factors Contributing to Vaginal Colonisation|journal=International Journal of Environmental Research and Public Health|volume=11|issue=7|year=2014|pages=6979–7000|issn=1660-4601|doi=10.3390/ijerph110706979|pmid=25014248|pmc=4113856}}
2. ^{{cite journal|doi=10.1099/ijs.0.000950-0|title=Emended description of Actinomyces naeslundii and descriptions of Actinomyces oris sp. nov. And Actinomyces johnsonii sp. nov., previously identified as Actinomyces naeslundii genospecies 1, 2 and WVA 963|journal=International Journal of Systematic and Evolutionary Microbiology|volume=59|issue=3|pages=509–16|year=2009|last1=Henssge|first1=U.|last2=Do|first2=T.|last3=Radford|first3=D. R.|last4=Gilbert|first4=S. C.|last5=Clark|first5=D.|last6=Beighton|first6=D.|pmid=19244431|pmc=2884933}}
3. ^{{cite web|url=http://www.emedicine.com/ped/byname/actinomycosis.htm |accessdate=22 May 2016 |title=Pediatric Actinomycosis |author=Quinonez JM |publisher=Medscape}}
4. ^{{cite web|url=https://helda.helsinki.fi/bitstream/handle/10138/20286/oralacti.pdf?sequence=2 |accessdate=24 July 2016 |title=Oral Actinomyces Species in Health and Disease: Identification, Occurrence and Importance of Early Colonization |publisher=National Public Health Institute, Helsinki, Finland |author=Nanna Sarkonen |date=August 2007}}

External links

  • [https://web.archive.org/web/20081223101645/http://cmr.jcvi.org/tigr-scripts/CMR/GenomePage.cgi?org=gan Actinomyces naeslundii MG1 Genome Page]
  • Type strain of Actinomyces naeslundii at BacDive - the Bacterial Diversity Metadatabase
{{Taxonbar|from=Q3911265}}{{Actinobacteria-stub}}

3 : Actinomycineae|Bacterial vaginosis|Bacteria described in 1951

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