“Sorbose 5-dehydrogenase (NADP+)”的意思、由来-开放百科全书

词条

Sorbose 5-dehydrogenase (NADP+)

释义

References

{{DISPLAYTITLE:Sorbose 5-dehydrogenase (NADP⁺)}}{{enzyme
| Name = sorbose 5-dehydrogenase (NADP⁺)
| EC_number = 1.1.1.123
| CAS_number = 37250-52-5
| IUBMB_EC_number = 1/1/1/123
| GO_code = 0050287
| image =
| width =
| caption =
}}

In enzymology, a sorbose 5-dehydrogenase (NADP⁺) ({{EC number|1.1.1.123}}) is an enzyme that catalyzes the chemical reaction

L-sorbose + NADP⁺ 5-dehydro-D-fructose + NADPH + H⁺

Thus, the two substrates of this enzyme are L-sorbose and NADP⁺, whereas its 3 products are 5-dehydro-D-fructose, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is L-sorbose:NADP⁺ 5-oxidoreductase. Other names in common use include 5-ketofructose reductase, 5-keto-D-fructose reductase, sorbose (nicotinamide adenine dinucleotide phosphate) dehydrogenase, reduced nicotinamide adenine dinucleotide phosphate-linked, reductase, and sorbose 5-dehydrogenase (NADP⁺).

References

{{cite journal |vauthors=Englard S, Kaysen G, Avigad G | date = 1970 | title = 5-keto-D-fructose. VI. A specific reduced nicotinamide adenine dinucleotide phosphate-linked reductase from yeast | journal = J. Biol. Chem. | volume = 245 | pages = 1311–8 | pmid = 4392628 | issue = 6 }}

3 : EC 1.1.1|NADPH-dependent enzymes|Enzymes of unknown structure

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