Take It from Me may refer to:

• Take It from Me (film), a 1937 British comedy film
• Take It from Me (1926 film), a film by William A. Seiter
• Take It from Me (album), a 1964 album by Terry Gibbs
• "Take It from Me" (Commodores song) (1987)
• "Take It from Me" (Girlfriend song) (1992)
• "Take It from Me" (Paul Brandt song) (1997)
• "Take It from Me" (Jordan Davis song) (2018)
• "Take It from Me", a 1983 song by Platinum Blonde from Standing in the Dark
• Take It from Me, a 1953–54 television series starring Jean Carroll

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