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词条 Yoshihiro Kawaoka
释义

  1. Controversial experiment

  2. Recognition

  3. Selected publications

  4. References

  5. External links

{{infobox person
|birth_date = {{birth date and age|1955|11|14}}
|birth_place = Kobe, Japan
|occupation = Virologist, professor at University of Wisconsin-Madison and University of Tokyo
|alma_mater = Hokkaido University
|known = Studies of influenza and Ebola viruses
}}{{nihongo|Yoshihiro Kawaoka|河岡 義裕|Kawaoka Yoshihiro|extra=born November 14, 1955}} is a virologist specializing in the study of the influenza and Ebola viruses. He holds a professorship in virology in the Department of Pathobiological Sciences at the University of Wisconsin-Madison, USA, and at the University of Tokyo, Japan.[1]

Following the Ebola outbreak of 2014 in West Africa, Kawaoka began development of an Ebola vaccine working in close coordination with Dr. Alhaji N'jai -- toxicologist at the University of Wisconsin -- and his non-profit organization Project 1808, Inc.

Controversial experiment

Kawaoka reinvented a new virus based on H5N1. For now, no known vaccine has been found. Despite the great disturbance he has caused, Kawaoka argued that "it is part of valuable scientific research".[2]

Dan Brown mentioned the experiment in his novel Inferno.[3]

Recognition

  • 2006 - Robert Koch Prize (with Peter Palese)[4]
  • 2011 - Medal with Purple Ribbon
  • 2013 - Members of the United States National Academy of Sciences
  • 2015 - Carlos J. Finlay Prize for Microbiology
  • 2016 - Japan Academy Prize

Selected publications

  • {{cite journal|last1=Jasenosky |first1=Luke D|last2=Neumann|first2=Gabriele|last3=Lukashevich|first3=Igor|last4=Kawaoka |first4=Y|title=Ebola virus vp40-induced particle formation and association with the lipid bilayer|journal=J Virol|volume=75|number=11|pages=5205–5214|doi=10.1128/JVI.75.11.5205-5214.2001|pmid=11333902|oclc=6965132858|url=http://jvi.asm.org/content/75/11/5205|access-date=2018-03-26|date=2001-06-01|pmc=114926}}
  • {{cite journal|last1=Watanabe|first1=Tokiko|last2=Watanabe|first2=Shinji|last3=Ito|first3=Hiroshi|last4=Kida|first4=Hiroshi|last5=Kawaoka|first5=Y|title= Influenza A virus can undergo multiple cycles of replication without m2 ion channel activity|journal=J Virol|volume=75| pages=5656–5662|url=http://jairo.nii.ac.jp/0003/00007115|access-date=2018-03-26|date=2001-06-15}}
  • {{cite journal|author1=Schultz-Cherry, S|author2= Dybdahl-Sissoko, N|author3=Neumann, G|author4= Kawaoka, Y|author5= Hinshaw VS|title= Influenza Virus NS1 Protein Induces Apoptosis in Cultured Cells|journal=J Virol|volume=75|pages=7875–7881|issn=0022-538X|oclc=120974346|url=http://jvi.asm.org/content/75/17/7875|access-date=2018-03-26|date= 2001-09-01}}
  • {{cite journal|author1=Hatta, M|author2=Gao, P|author3=Halfmann, P|author4=Kawaoka, Y|title= Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses|journal=Science|number= 298|pages=1840–1842|issn=0036-8075|oclc=95118961|date= 2001-09-07}}
  • {{cite journal|last1=Goto|first1=Hideo|last2=Wells|first2=Krisna|last3=Takada|first3=Ayato|last4= Kawaoka|first4=Y.|title=Plasminogen-binding activity of neuraminidase determines the pathogenicity of influenza A virus|journal=J Virol|volume=75|pages=9297–9301|issn=0022-538X|oclc=6965138857|url=http://jvi.asm.org/content/75/19/9297|access-date=2018-03-26|archive-url=https://web.archive.org/web/20180326181519/http://jvi.asm.org/content/75/19/9297|archive-date=2018-03-26|date=2001-10-01}}
  • {{cite journal|last1=Kobasa|first1=Darwyn|last2=Wells|first2=Krisna|last3= Kawaoka|first3= Yoshihiro|title= Amino Acids Responsible for the Absolute Sialidase Activity of the Influenza A Virus Neuraminidase: Relationship to Growth in Duck Intestine|journal=J Virol|volume=75|pages=11773–11780|oclc=4639538185|url=http://jvi.asm.org/content/75/23/11773|accessdate=2018-03-26|archive-url=https://web.archive.org/web/20180326180300/http://jvi.asm.org/content/75/23/11773|archive-date=2018-03-26|date=2001-12-01}}
  • {{cite book|title=Influenza Virus : Methods and Protocols|volume=865|last1=Kawaoka|first=Y|last2=Neumann|first2=Gabriele|publisher=Springer|series=Methods in Molecular Biology, Methods and Protocols, 865|year=2012|doi=10.1007/978-1-61779-621-0|isbn=978-1-61779-620-3}}
  • {{cite journal|title=Ebora shukketsu netsu no seiatsu ni mukete : Wakuchin kaihatsu to shierareone de no kenkyu|trans-title=Control of Ebola hemorrhagic fever : vaccine development and our Ebola project in Sierra Leone|language=ja|last1=Watanabe|first1=Tokiko|last2=Kawaoka|first2=Yoshihiro|journal=Virus|volume=66|number=1|pages=53–62|issn=0042-6857|oclc=6807788600|date=June 2016}}

References

1. ^Influenza 2013: Professor Yoshihiro Kawaoka{{dead link|date=July 2016 |bot=InternetArchiveBot |fix-attempted=yes }} (accessed 7 November 2013)
2. ^{{cite news |author = Guy Walters |url = http://www.dailymail.co.uk/sciencetech/article-2678732/Are-mad-let-maverick-scientist-create-virus-wipe-400-million-people.html |title = Are we mad to have let a maverick scientist create a virus that could wipe out 400 million people? |publisher = MailOnline |date = 3 July 2014 |accessdate = 4 July 2014}}
3. ^Dan Burstein, Secrets of Inferno: In the Footsteps of Dante and Dan Brown. Story Plant, 2013.
4. ^Robert-Koch-Stiftung: Robert Koch Award. Retrieved 4 July 2014.

External links

  • Robert Koch Award lecture: New possibilities in the fight against influenza (3 November 2006)
{{Authority control}}{{DEFAULTSORT:Kawaoka, Yoshihiro}}{{japan-scientist-stub}}

12 : Living people|1955 births|People from Kobe|Influenza researchers|American virologists|Japanese virologists|Japanese microbiologists|University of Wisconsin–Madison faculty|University of Tokyo faculty|Hokkaido University alumni|Recipients of the Medal of Honor (Japan)|Members of the United States National Academy of Sciences

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