| 词条 | Artificially Expanded Genetic Information System |
| 释义 |
The system uses twelve different nucleobases in its genetic code. These include the four canonical nucleobases found in DNA (adenine, cytosine, guanine and thymine) plus eight synthetic nucleobases).[1][2][3][4][5] AEGIS includes S:B, Z:P, V:J and K:X base pairs.[6] See also{{div col|colwidth=30em}}
References1. ^{{cite journal|last1=Yang|first1=Z.|last2=Hutter|first2=D.|last3=Sheng|first3=P.|last4=Sismour|first4=A. M.|last5=Benner|first5=S. A.|title=Artificially expanded genetic information system: a new base pair with an alternative hydrogen bonding pattern|journal=Nucleic Acids Research|date=29 October 2006|volume=34|issue=21|pages=6095–6101|doi=10.1093/nar/gkl633|url=http://nar.oxfordjournals.org/content/34/21/6095.long|accessdate=5 July 2016|pmid=17074747|pmc=1635279}} {{genetics-stub}}2. ^{{cite journal|last1=Benner|first1=SA|last2=Hutter|first2=D|last3=Sismour|first3=AM|title=Synthetic biology with artificially expanded genetic information systems. From personalized medicine to extraterrestrial life.|journal=Nucleic Acids Research. Supplement |volume=3|date=1 September 2003|issue=3|pages=125–6|pmid=14510412|url=http://nass.oxfordjournals.org/content/3/1/125.long|accessdate=5 July 2016|doi=10.1093/nass/3.1.125}} 3. ^{{cite journal|last1=Benner|first1=Steven A.|title=Defining Life|journal=Astrobiology|date=December 2010|volume=10|issue=10|pages=1021–1030|doi=10.1089/ast.2010.0524|bibcode=2010AsBio..10.1021B|pmc=3005285|pmid=21162682}} 4. ^{{cite news|last1=Klotz|first1=Irene|title=Synthetic life form grows in Florida lab|url=http://www.nbcnews.com/id/29430688/|accessdate=5 July 2016|work=Science|date=February 27, 2009}} 5. ^1 {{cite news|last1=Lloyd|first1=Robin|title=New Artificial DNA Points to Alien Life|url=http://www.livescience.com/3332-artificial-dna-points-alien-life.html|accessdate=5 July 2016|work=LiveScience|date=February 14, 2009}} 6. ^{{Cite journal |pmc = 4142867|year = 2014|last1 = Bradley|first1 = K. M.|title = OligArch: A software tool to allow artificially expanded genetic information systems (AEGIS) to guide the autonomous self-assembly of long DNA constructs from multiple DNA single strands|journal = Beilstein Journal of Organic Chemistry|volume = 10|pages = 1826–1833|last2 = Benner|first2 = S. A.|pmid = 25161743|doi = 10.3762/bjoc.10.192}} 3 : Astrobiology|Biotechnology|DNA |
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