| 词条 | Hartmut Michel |
| 释义 |
|name = Hartmut Michel |image = Michel, Hartmut (1948).jpg |image_size = |caption = Hartmut Michel in 2013 |birth_date = {{Birth date and age|df=y|1948|7|18}} |birth_place = Ludwigsburg |death_date = |death_place = |residence = |citizenship = |nationality = German |ethnicity = |field = Biochemistry |work_institutions = Max Planck Institute for Biophysics |alma_mater = University of Tübingen |doctoral_advisor = |doctoral_students = |known_for = Crystallisation of membrane proteins |website ={{URL|http://www.biophys.mpg.de/en/michel.html}} |influences = |influenced = |prizes = {{Plainlist|
|religion = |footnotes = |signature = |spouse = Elena Olkhova }}Hartmut Michel (born 18 July 1948) is a German biochemist, who received the 1988 Nobel Prize in Chemistry.[2][3][4][5] Education and early lifeHe was born on 18 July 1948 in Ludwigsburg. After compulsory military service, he studied biochemistry at the University of Tübingen, working for his final year at Dieter Oesterhelt's laboratory on ATPase activity of halobacteria. Career and researchHartmut later{{when|date=October 2015}} worked on the crystallisation of membrane proteins - essential for their structure elucidation by X-ray crystallography. He received the Nobel Prize jointly with Johann Deisenhofer and Robert Huber in 1988. Together with Michel and Huber, Deisenhofer determined the three-dimensional structure of a protein complex found in certain photosynthetic bacteria. This membrane protein complex, called a photosynthetic reaction center, was known to play a crucial role in initiating a simple type of photosynthesis. Between 1982 and 1985, the three scientists used X-ray crystallography to determine the exact arrangement of the more than 10,000 atoms that make up the protein complex. Their research increased the general understanding of the mechanisms of photosynthesis, revealed similarities between the photosynthetic processes of plants and bacteria and established a methodology for crystallising membrane proteins.[6] Since 1987 he has been director of the Molecular Membrane Biology department at the Max Planck Institute for Biophysics in Frankfurt am Main, Germany, and professor of biochemistry at the Goethe University Frankfurt. Awards and honoursIn 1986, he received the Gottfried Wilhelm Leibniz Prize of the Deutsche Forschungsgemeinschaft, which is the highest honour awarded in German research. In 1988, he received the Nobel Prize in Chemistry. He received the Bijvoet Medal at the Bijvoet Center for Biomolecular Research of Utrecht University in 1989.[7] He became a foreign member of the Royal Netherlands Academy of Arts and Sciences in 1995.[8] He was elected a Foreign Member of the Royal Society (ForMemRS) in 2005.[1] References1. ^1 {{cite web|archiveurl=https://web.archive.org/web/20151026223249/https://royalsociety.org/people/hartmut-michel-11948/|archivedate=2015-10-26|url=https://royalsociety.org/people/hartmut-michel-11948/|publisher=Royal Society|location=London|title=Professor Hartmut Michel ForMemRS}} {{Nobel Prize in Chemistry Laureates 1976-2000}}{{FRS 2005}}{{Authority control}}{{Use dmy dates|date=April 2017}}{{DEFAULTSORT:Michel, Hartmut}}{{Germany-biochemist-stub}}2. ^Autobiographical information on Hartmut at www.nobel.org 3. ^Structural genomics on selected families of secondary active transporters, project page at the Frankfurt University 4. ^{{Cite journal | doi = 10.1038/376660a0| title = Structure at 2.8 Å resolution of cytochrome c oxidase from Paracoccus denitrificans| journal = Nature| volume = 376| issue = 6542| pages = 660| year = 1995| last1 = Iwata | first1 = S. | last2 = Ostermeier | first2 = C. | last3 = Ludwig | first3 = B. | last4 = Michel | first4 = H. }} 5. ^{{Cite journal | doi = 10.1016/S0022-2836(84)80011-X| title = X-ray structure analysis of a membrane protein complex| journal = Journal of Molecular Biology| volume = 180| issue = 2| pages = 385| year = 1984| last1 = Deisenhofer | first1 = J.| last2 = Epp | first2 = O.| last3 = Miki | first3 = K.| last4 = Huber | first4 = R.| last5 = Michel | first5 = H.}} 6. ^{{Cite journal | doi = 10.1038/318618a0| title = Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution| journal = Nature| volume = 318| issue = 6047| pages = 618| year = 1985| last1 = Deisenhofer | first1 = J.| authorlink1 = Johann Deisenhofer| last2 = Epp | first2 = O.| last3 = Miki | first3 = K.| last4 = Huber | first4 = R.| authorlink4 = Robert Huber| last5 = Michel | first5 = H.| authorlink5 = Hartmut Michel}} 7. ^{{cite web|url=http://bijvoet-center.eu/bijvoet-medal/|title=Bijvoet Medal|publisher= Bijvoet Center for Biomolecular Research|accessdate=2017-09-12}} 8. ^{{cite web|author= |url=https://www.knaw.nl/en/members/foreign-members/4549 |archive-url=https://web.archive.org/web/20160213195237/https://www.knaw.nl/en/members/foreign-members/4549 |title=H. Michel |publisher=Royal Netherlands Academy of Arts and Sciences |date= |archive-date=13 February 2016 |accessdate=13 February 2016}} 16 : 1948 births|Members of the European Molecular Biology Organization|Members of the United States National Academy of Sciences|Living people|German biochemists|Nobel laureates in Chemistry|German Nobel laureates|Gottfried Wilhelm Leibniz Prize winners|Foreign Members of the Royal Society|Foreign members of the Chinese Academy of Sciences|Members of the Royal Netherlands Academy of Arts and Sciences|Max Planck Society people|Goethe University Frankfurt faculty|Scientists from Frankfurt|Researchers of photosynthesis|Bijvoet Medal recipients |
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