| 释义 |
- Clinical significance
- References
- Further reading
{{Infobox_gene}}Glucosamine-6-phosphate deaminase 2 also known as GNPDA2 is an enzyme that in humans is encoded by the GNPDA2 gene.[1] Clinical significance Variants of the GNPDA2 gene may be associated with obesity.[2][3][4] References1. ^{{cite journal |vauthors=Arreola R, Valderrama B, Morante ML, Horjales E | title = Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study | journal = FEBS Lett. | volume = 551 | issue = 1–3 | pages = 63–70 |date=September 2003 | pmid = 12965206 | doi = 10.1016/S0014-5793(03)00896-2| url = }}
2. ^{{cite journal |vauthors=Zhao J, Bradfield JP, Li M |title=The role of obesity-associated loci identified in genome wide association studies in the determination of pediatric BMI |journal=Obesity (Silver Spring) |volume= 17|issue= 12|pages= 2254–7|date=May 2009 |pmid=19478790 |doi=10.1038/oby.2009.159 |pmc=2860782|display-authors=etal}}
3. ^{{cite journal |vauthors=Renström F, Payne F, Nordström A, Brito EC, Rolandsson O, Hallmans G, Barroso I, Nordström P, Franks PW | title = Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden | journal = Hum. Mol. Genet. | volume = 18 | issue = 8 | pages = 1489–96 |date=April 2009 | pmid = 19164386 | pmc = 2664142 | doi = 10.1093/hmg/ddp041 | url = }}
4. ^{{cite journal |vauthors=Willer CJ, Speliotes EK, Loos RJ | title = Six new loci associated with body mass index highlight a neuronal influence on body weight regulation | journal = Nat. Genet. | volume = 41 | issue = 1 | pages = 25–34 |date=January 2009 | pmid = 19079261 | doi = 10.1038/ng.287 | url = | pmc = 2695662 |display-authors=etal}}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Bauer F, Elbers CC, Adan RA |title=Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference |journal=Am. J. Clin. Nutr. |volume=90 |issue= 4 |pages= 951–9 |year= 2009 |pmid= 19692490 |doi= 10.3945/ajcn.2009.27781 |display-authors=etal}}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
- {{cite journal |vauthors=Haupt A, Thamer C, Heni M |title=Novel Obesity Risk Loci Do Not Determine Distribution of Body Fat Depots: A Whole-body MRI/MRS study |journal=Obesity (Silver Spring) |volume= 18|issue= 6|pages= 1212–7 |year= 2009 |pmid= 19910938 |doi= 10.1038/oby.2009.413 |display-authors=etal}}
- {{cite journal |vauthors=Li S, Zhao JH, Luan J |title=Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies |journal=Am. J. Clin. Nutr. |volume=91 |issue= 1 |pages= 184–90 |year= 2010 |pmid= 19812171 |doi= 10.3945/ajcn.2009.28403 |display-authors=etal}}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241 |display-authors=etal}}
- {{cite journal |vauthors=Brandys MK, van Elburg AA, Loos RJ |title=Are recently identified genetic variants regulating BMI in the general population associated with anorexia nervosa? |journal=Am. J. Med. Genet. B Neuropsychiatr. Genet. |volume=153B |issue= 2 |pages= 695–9 |year= 2010 |pmid= 19746409 |doi= 10.1002/ajmg.b.31026 |display-authors=etal}}
- {{cite journal |vauthors=Renström F, Payne F, Nordström A |title=Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden |journal=Hum. Mol. Genet. |volume=18 |issue= 8 |pages= 1489–96 |year= 2009 |pmid= 19164386 |doi= 10.1093/hmg/ddp041 |pmc=2664142 |display-authors=etal}}
- {{cite journal |vauthors=He M, Cornelis MC, Franks PW |title=Obesity Genotype Score and Cardiovascular Risk in Women with Type 2 Diabetes |journal=Arterioscler. Thromb. Vasc. Biol. |volume=30 |issue= 2 |pages= 327–32 |year= 2010 |pmid= 19910641 |doi= 10.1161/ATVBAHA.109.196196 |pmc=3061473 |display-authors=etal}}
- {{cite journal |vauthors=Barbe L, Lundberg E, Oksvold P |title=Toward a confocal subcellular atlas of the human proteome |journal=Mol. Cell. Proteomics |volume=7 |issue= 3 |pages= 499–508 |year= 2008 |pmid= 18029348 |doi= 10.1074/mcp.M700325-MCP200 |display-authors=etal}}
- {{cite journal |vauthors=Hotta K, Nakamura M, Nakamura T |title=Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population |journal=J. Hum. Genet. |volume=54 |issue= 12 |pages= 727–31 |year= 2009 |pmid= 19851340 |doi= 10.1038/jhg.2009.106 |display-authors=etal}}
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