| 释义 |
- Function
- See also
- References
- Further reading
{{Infobox_gene}}High mobility group nucleosome-binding domain-containing protein 4 is a transcription factor that in humans is encoded by the HMGN4 gene.[1][2] Function The protein encoded by this gene, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Transcript variants utilizing alternative polyadenylation signals exist for this gene.[1] See also References 1. ^1 {{cite web | title = Entrez Gene: high mobility group nucleosomal binding domain 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10473| accessdate = }}
2. ^{{cite journal |vauthors=Birger Y, Ito Y, West KL, Landsman D, Bustin M | title = HMGN4, a newly discovered nucleosome-binding protein encoded by an intronless gene | journal = DNA Cell Biol. | volume = 20 | issue = 5 | pages = 257–64 |date=May 2001 | pmid = 11410162 | doi = 10.1089/104454901750232454 | url = | issn = }}
Further reading {{refbegin | 2}}- {{cite journal |vauthors=Ruddy DA, Kronmal GS, Lee VK, etal |title=A 1.1-Mb transcript map of the hereditary hemochromatosis locus. |journal=Genome Res. |volume=7 |issue= 5 |pages= 441–56 |year= 1997 |pmid= 9149941 |doi= 10.1101/gr.7.5.441}}
- {{cite journal |vauthors=Mungall AJ, Palmer SA, Sims SK, etal |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241}}
- {{cite journal |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 |pmc=1356129}}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |pmc=528928}}
{{refend}}{{Transcription factors|g4}}{{gene-6-stub}} 1 : Transcription factors |