| 词条 | Magnesium responsive RNA element |
| 释义 |
| Name = Magnesium responsive RNA element | image = MGsensor SS.png | width = | caption = | Symbol = Mg sensor | AltSymbols = | Rfam = RF01056 | miRBase = | miRBase_family = | RNA_type = Cis-regulatory element | Tax_domain = Enterobacteriales | GO = 0032026 | SO = | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} The Magnesium responsive RNA element, not to be confused with the completely distinct M-box riboswitch, is a cis-regulatory element that regulates the expression of the magnesium transporter protein MgtA. It is located in the 5' UTR of this gene.[1] The mechanism for the potential magnesium-sensing capacity of this RNA is still unclear, though a recent report suggests that the RNA element targets the mgtA transcript for degradation by RNase E when cells are grown in high Mg2+ environments.[2] References1. ^{{cite journal |vauthors=Groisman EA, Cromie MJ, Shi Y, Latifi T |title=A Mg2+-responding RNA that controls the expression of a Mg2+ transporter. |journal=Cold Spring Harb Symp Quant Biol |volume=71 |issue= |pages=251–8 |year=2006 |pmid=17381304 |doi=10.1101/sqb.2006.71.005}} 2. ^{{cite journal |vauthors=Spinelli SV, Pontel LB, García Véscovi E, Soncini FC |title=Regulation of magnesium homeostasis in Salmonella: Mg(2+) targets the mgtA transcript for degradation by RNase E. |journal=FEMS Microbiol Lett |volume=280 |issue=2 |pages=226–34 |year=2008 |pmid=18248433 |doi=10.1111/j.1574-6968.2008.01065.x}} External links
1 : Cis-regulatory RNA elements |
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