| 释义 |
- Function
- References
- Further reading
{{about|the human gene|the communication standard|Standard Marine Communication Phrases|the video game|Sonic Mega Collection#Sonic Mega Collection Plus}}{{Infobox_gene}}Sperm mitochondrial-associated cysteine-rich protein is a protein that in humans is encoded by the SMCP gene.[1][2] Function Sperm mitochondria differ in morphology and subcellular localization from those of somatic cells. They are elongated, flattened, and arranged circumferentially to form a helical coiled sheath in the midpiece of the sperm flagellum. The protein encoded by this gene localizes to the capsule associated with the mitochondrial outer membranes and is thought to function in the organization and stabilization of the helical structure of the sperm's mitochondrial sheath.[2] References 1. ^{{cite journal | vauthors = Aho H, Schwemmer M, Tessman D, Murphy D, Mattei G, Engel W, Adham IM | title = Isolation, expression, and chromosomal localization of the human mitochondrial capsule selenoprotein gene (MCSP) | journal = Genomics | volume = 32 | issue = 2 | pages = 184–90 | date = Mar 1996 | pmid = 8833144 | pmc = | doi = 10.1006/geno.1996.0104 }}
2. ^1 {{cite web | title = Entrez Gene: SMCP sperm mitochondria-associated cysteine-rich protein| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4184| accessdate = }}
Further reading {{refbegin|33em}}- {{cite journal | vauthors = Behne D, Kyriakopoulos A | title = Mammalian selenium-containing proteins | journal = Annual Review of Nutrition | volume = 21 | issue = | pages = 453–73 | year = 2001 | pmid = 11375445 | doi = 10.1146/annurev.nutr.21.1.453 }}
- {{cite journal | vauthors = Karimpour I, Cutler M, Shih D, Smith J, Kleene KC | title = Sequence of the gene encoding the mitochondrial capsule selenoprotein of mouse sperm: identification of three in-phase TGA selenocysteine codons | journal = DNA and Cell Biology | volume = 11 | issue = 9 | pages = 693–9 | date = Nov 1992 | pmid = 1418626 | doi = 10.1089/dna.1992.11.693 }}
- {{cite journal | vauthors = Saaranen M, Suistomaa U, Vanha-Perttula T | title = Semen selenium content and sperm mitochondrial volume in human and some animal species | journal = Human Reproduction | volume = 4 | issue = 3 | pages = 304–8 | date = Apr 1989 | pmid = 2715306 | doi = 10.1093/oxfordjournals.humrep.a136893 }}
- {{cite journal | vauthors = Cataldo L, Baig K, Oko R, Mastrangelo MA, Kleene KC | title = Developmental expression, intracellular localization, and selenium content of the cysteine-rich protein associated with the mitochondrial capsules of mouse sperm | journal = Molecular Reproduction and Development | volume = 45 | issue = 3 | pages = 320–31 | date = Nov 1996 | pmid = 8916043 | doi = 10.1002/(SICI)1098-2795(199611)45:3<320::AID-MRD9>3.0.CO;2-U }}
- {{cite journal | vauthors = Herr JC, Thomas D, Bush LA, Coonrod S, Khole V, Howards SS, Flickinger CJ | title = Sperm mitochondria-associated cysteine-rich protein (SMCP) is an autoantigen in Lewis rats | journal = Biology of Reproduction | volume = 61 | issue = 2 | pages = 428–35 | date = Aug 1999 | pmid = 10411523 | doi = 10.1095/biolreprod61.2.428 }}
- {{cite journal | vauthors = Nayernia K, Adham IM, Burkhardt-Göttges E, Neesen J, Rieche M, Wolf S, Sancken U, Kleene K, Engel W | title = Asthenozoospermia in mice with targeted deletion of the sperm mitochondrion-associated cysteine-rich protein (Smcp) gene | journal = Molecular and Cellular Biology | volume = 22 | issue = 9 | pages = 3046–52 | date = May 2002 | pmid = 11940662 | pmc = 133774 | doi = 10.1128/MCB.22.9.3046-3052.2002 }}
- {{cite journal | vauthors = Hawthorne SK, Goodarzi G, Bagarova J, Gallant KE, Busanelli RR, Olend WJ, Kleene KC | title = Comparative genomics of the sperm mitochondria-associated cysteine-rich protein gene | journal = Genomics | volume = 87 | issue = 3 | pages = 382–91 | date = Mar 2006 | pmid = 16325371 | doi = 10.1016/j.ygeno.2005.09.010 }}
- {{cite journal | vauthors = Yatsenko AN, Roy A, Chen R, Ma L, Murthy LJ, Yan W, Lamb DJ, Matzuk MM | title = Non-invasive genetic diagnosis of male infertility using spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization | journal = Human Molecular Genetics | volume = 15 | issue = 23 | pages = 3411–9 | date = Dec 2006 | pmid = 17047026 | doi = 10.1093/hmg/ddl417 }}
{{refend}}{{gene-1-stub}} 1 : Selenoproteins |