请输入您要查询的百科知识:

 

词条 Microneme
释义

  1. See also

  2. References

Micronemes are secretory organelles, possessed by parasitic apicomplexans. Micronemes are located on the apical third of the protozoan body. They are surrounded by a typical unit membrane. On electron microscopy they have an electron-dense matrix due to the high protein content. They are specialized secretory organelles important for host-cell invasion and gliding motility.[2]

These organelles secrete several proteins such as the Plasmodium falciparum apical membrane antigen-1, or PfAMA1, and Erythrocyte family antigen, or EBA, family proteins. These proteins specialize in binding to erythrocyte surface receptors and facilitating erythrocyte entry. Only by this initial chemical exchange can the parasite enter into the erythrocyte via actin-myosin motor complex.{{Citation needed|date=August 2018}}

It has been posited that this organelle works cooperatively with its counterpart organelle, the rhoptry, which also is a secretory organelle. It is possible that, while the microneme initiates erythrocyte-binding, the rhoptry secretes proteins to create the PVM, or the parasitophorous vacuole membrane, in which the parasite can survive and reproduce.[3]

See also

  • Dense granule
  • Rhoptry

References

1. ^{{cite journal|last1=Rigoulet|first1=Jacques|last2=Hennache|first2=Alain|last3=Lagourette|first3=Pierre|last4=George|first4=Catherine|last5=Longeart|first5=Loïc|last6=Le Net|first6=Jean-Loïc|last7=Dubey|first7=Jitender P.|title=Toxoplasmosis in a bar-shouldered dove (Geopelia humeralis) from the Zoo of Clères, France|journal=Parasite|volume=21|year=2014|pages=62|issn=1776-1042|doi=10.1051/parasite/2014062|pmid=25407506|pmc=4236686}} {{open access}}
2. ^{{cite journal |last1=Black |first1=MW |last2=Boothroyd |first2=JC |title=Lytic cycle of Toxoplasma gondii |journal=Microbiology and Molecular Biology Reviews |date=September 2000 |volume=64 |issue=3 |pages=607–23 |pmid=10974128}}
3. ^{{cite journal |last1=Lingelbach |first1=K |last2=Joiner |first2=KA |title=The parasitophorous vacuole membrane surrounding Plasmodium and Toxoplasma: an unusual compartment in infected cells |journal=Journal of Cell Science |date=June 1998 |volume=111 ( Pt 11) |pages=1467–75 |pmid=9580555}}
{{Protist}}

1 : Parasitology

随便看

 

开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。

 

Copyright © 2023 OENC.NET All Rights Reserved
京ICP备2021023879号 更新时间:2024/9/22 12:55:00