词条 | Zorubicin |
释义 | {{Drugbox | verifiedrevid = 442303628 | IUPAC_name = (E)-N'-(1-((2S,4S)-4-((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylidene)benzohydrazide | image = Zorubicin.png | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = Rx-only | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number = 54083-22-6 | ATC_prefix = L01 | ATC_suffix = DB05 | ATC_supplemental = | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | UNII_Ref = {{fdacite|correct|FDA}} | UNII = V25F9362OP | PubChem = 9595290 | ChemSpiderID = 7869436 | StdInChI = 1S/C34H35N3O10/c1-15-28(38)20(35)12-23(46-15)47-22-14-34(44,16(2)36-37-33(43)17-8-5-4-6-9-17)13-19-25(22)32(42)27-26(30(19)40)29(39)18-10-7-11-21(45-3)24(18)31(27)41/h4-11,15,20,22-23,28,38,40,42,44H,12-14,35H2,1-3H3,(H,37,43)/b36-16+/t15-,20-,22-,23-,28+,34-/m0/s1 | StdInChIKey = FBTUMDXHSRTGRV-ALTNURHMSA-N | chemical_formula = | C=34 | H=35 | N=3 | O=10 | molecular_weight = 645.65 g/mol | smiles = OC1=C(C(C4=C(C=CC=C4OC)C3=O)=O)C3=C(O)C2=C1[C@@H](O[C@]5([H])O[C@@H](C)[C@@H](O)[C@@H](N)C5)C[C@@](/[C@@](C)=N/NC(C6=CC=CC=C6)=O)(O)C2 }} Zorubicin (INN) is an anthracycline. {{Chemotherapeutic agents}}{{antineoplastic-drug-stub}} 5 : Anthracyclines|Topoisomerase inhibitors|Hydrazides|Phenols|Phenol ethers |
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