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词条 3,5-Dimethylpiperidine
释义

  1. References

{{chembox
| verifiedrevid = 399204910
| Name = 3,5-Dimethylpiperidine
| ImageFile = 3,5-dimethylpiperidine.svg
| ImageSize =
| ImageName = Structure of 3,5-dimethylpiperidine
| PIN = 3,5-Dimethylpiperidine
| OtherNames = 3,5-Lupetidine
|Section1={{Chembox Identifiers
| PubChem = 118259
| ChemSpiderID = 105689
| SMILES = CC1CC(CNC1)C
| StdInChI = 1S/C7H15N/c1-6-3-7(2)5-8-4-6/h6-8H,3-5H2,1-2H3
| StdInChIKey = IDWRJRPUIXRFRX-UHFFFAOYSA-N
| CASNo = 35794-11-7
| RTECS =
|Section2={{Chembox Properties
| C=7 | H=15 | N=1
| Appearance = Colorless liquid
| Density = 0.853 g/mL (mixture)
| Solubility = Low
| Solvent = other solvents
| SolubleOther = Most organic solvents
| MeltingPt =
| BoilingPtC = 144
| pKb =
| RefractIndex = 1.4454
|Section3={{Chembox Structure
| Dipole =
|Section7={{Chembox Hazards
| ExternalSDS =
| MainHazards = Flammable
| FlashPtC = 33
| RPhrases =
| SPhrases =
|Section8={{Chembox Related
| OtherCompounds = 2,6-Dimethylpiperidine
Piperidine
}}

3,5-Dimethylpiperidines are chemical compounds with the formula C5H8(CH3)2NH. Two diastereomers exist: the achiral R,S isomer and the chiral R,R/S,S enantiomeric pair. 3,5-Dimethylpiperidine is a precursor to tibric acid.

The compound is typically prepared by hydrogenation of 3,5-dimethylpyridine. Both diastereomers also arise from the reduction of 3,5-dimethylpyridine with lithium triethylborohydride.[1]

References

1. ^{{cite journal|title=Reduction of isoquinoline and pyridine-containing heterocycles with lithium triethylborohydride (Super-Hydride)|author1=Blough, Bruce E.|author2=Carroll|author3=F. Ivy|journal=Tetrahedron Letters|year=1993|volume=34|pages=7239-42|doi=10.1016/S0040-4039(00)79297-5}}
{{DEFAULTSORT:Dimethylpiperidine, 3,5-}}

1 : Piperidines

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