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词条 Hydrogenase (NAD+, ferredoxin)
释义

  1. References

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{{Infobox enzyme
| Name = Hydrogenase (NAD+, ferredoxin)
| EC_number = 1.12.1.4
| CAS_number =
| IUBMB_EC_number = 1/12/1/4
| GO_code =
| image =
| width =
| caption =
}}Hydrogenase (NAD+, ferredoxin) ({{EC number|1.12.1.4}}, bifurcating [FeFe] hydrogenase) is an enzyme with systematic name hydrogen:NAD+, ferredoxin oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

2 H2 + NAD+ + 2 oxidized ferredoxin 5 H+ + NADH + 2 reduced ferredoxin

The enzyme from Thermotoga maritima contains a [Fe-Fe] cluster (H-cluster) and iron-sulfur clusters. I

References

1. ^{{cite journal | vauthors = Verhagen MF, O'Rourke T, Adams MW | title = The hyperthermophilic bacterium, Thermotoga maritima, contains an unusually complex iron-hydrogenase: amino acid sequence analyses versus biochemical characterization | journal = Biochimica et Biophysica Acta | volume = 1412 | issue = 3 | pages = 212–29 | date = August 1999 | pmid = 10482784 | doi = 10.1016/s0005-2728(99)00062-6 }}
2. ^{{cite journal | vauthors = Schut GJ, Adams MW | title = The iron-hydrogenase of Thermotoga maritima utilizes ferredoxin and NADH synergistically: a new perspective on anaerobic hydrogen production | journal = Journal of Bacteriology | volume = 191 | issue = 13 | pages = 4451–7 | date = July 2009 | pmid = 19411328 | pmc = 2698477 | doi = 10.1128/JB.01582-08 }}

External links

  • {{MeshName|Hydrogenase+(NAD+,+ferredoxin)}}
{{Hydrogen oxidoreductases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 1.12.1

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