| 词条 | Microbial dark matter |
| 释义 |
Microbial dark matter[1][2] comprises the vast majority of microbial organisms (usually bacteria and archaea) that biologists are unable to culture in lab due to lack of knowledge or ability to supply the required growth conditions. Microbial dark matter is unrelated to the dark matter of physics and cosmology, but is so-called for the difficulty in effectively studying it as a result of its inability to be cultured by current methods. It is hard to estimate its relative magnitude, but the accepted gross estimate is that less than one percent of microbial species in a given ecological niche is culturable. In recent years effort is being put to decipher more of the microbial dark matter by means of learning their genome DNA sequence from environmental samples[3] and then by gaining insights to their metabolism from their sequenced genome, promoting the knowledge required for their cultivation. See also
References1. ^{{cite journal|last1=Filee|first1=J.|last2=Tetart|first2=F.|last3=Suttle|first3=C. A.|last4=Krisch|first4=H. M.|title=Marine T4-type bacteriophages, a ubiquitous component of the dark matter of the biosphere|journal=Proceedings of the National Academy of Sciences|volume=102|issue=35|year=2005|pages=12471–12476|issn=0027-8424|doi=10.1073/pnas.0503404102|pmid=16116082|pmc=1194919}} 2. ^{{cite news |author=University of Tennessee at Knoxville |title=Study: Microbial dark matter dominates Earth's environments |url=https://www.eurekalert.org/pub_releases/2018-09/uota-smd092518.php |date=25 September 2018 |work=Eurekalert! |accessdate=26 September 2018 }} 3. ^{{cite journal|last1=Hedlund|first1=Brian P.|last2=Dodsworth|first2=Jeremy A.|last3=Murugapiran|first3=Senthil K.|last4=Rinke|first4=Christian|last5=Woyke|first5=Tanja|title=Impact of single-cell genomics and metagenomics on the emerging view of extremophile "microbial dark matter"|journal=Extremophiles|volume=18|issue=5|year=2014|pages=865–875|issn=1431-0651|doi=10.1007/s00792-014-0664-7}} External links
3 : Molecular biology|Molecular biology techniques|Microbiology |
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