| 词条 | O-sialoglycoprotein endopeptidase |
| 释义 |
| Name = O-sialoglycoprotein endopeptidase | EC_number = 3.4.24.57 | CAS_number = 129430-53-1 | IUBMB_EC_number = 3/4/24/57 | GO_code = | image = | width = | caption = }}O-sialoglycoprotein endopeptidase ({{EC number|3.4.24.57}}, glycoprotease, glycophorin A proteinase, glycoproteinase, sialoglycoprotease, sialoglycoproteinase, "OSGE") is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction Hydrolysis of O-sialoglycoproteins; cleaves -Arg31-Asp- bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated This enzyme is secreted by the bacterium Pasteurella haemolytica. References1. ^{{cite journal | vauthors = Abdullah KM, Lo RY, Mellors A | title = Cloning, nucleotide sequence, and expression of the Pasteurella haemolytica A1 glycoprotease gene | journal = Journal of Bacteriology | volume = 173 | issue = 18 | pages = 5597–603 | date = September 1991 | pmid = 1885539 | pmc = 208286 | doi = 10.1128/jb.173.18.5597-5603.1991 }} 2. ^{{cite journal | vauthors = Abdullah KM, Udoh EA, Shewen PE, Mellors A | title = A neutral glycoprotease of Pasteurella haemolytica A1 specifically cleaves O-sialoglycoproteins | journal = Infection and Immunity | volume = 60 | issue = 1 | pages = 56–62 | date = January 1992 | pmid = 1729196 | pmc = 257502 }} 3. ^{{cite journal | vauthors = Sutherland DR, Abdullah KM, Cyopick P, Mellors A | title = Cleavage of the cell-surface O-sialoglycoproteins CD34, CD43, CD44, and CD45 by a novel glycoprotease from Pasteurella haemolytica | journal = Journal of Immunology | volume = 148 | issue = 5 | pages = 1458–64 | date = March 1992 | pmid = 1371528 }} External links
1 : EC 3.4.24 |
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