| 词条 | Tectitethya crypta |
| 释义 |
| name = | image = | regnum = Animalia | phylum = Porifera | classis = Demospongiae | subclassis = | ordo = Hadromerida | familia = Tethyidae | genus = Tectitethya | species = T. crypta | binomial = Tectitethya crypta | binomial_authority = (de Laubenfels, 1949) | synonyms = Cryptotethya crypta de Laubenfels, 1949 Tethya crypta (de Laubenfels, 1949) | synonyms_ref = [1] }}Tectitethya crypta (formerly known as Cryptotethya crypta and Tethya crypta) is a species of demosponge belonging to the family Tethyidae.[1] It is a massive, shallow-water sponge found in the Caribbean Sea.[2][3] Oftentimes, it is covered in sand and algae.[2][3] The nucleosides spongothymidine and spongouridine were isolated from this sponge, providing the basis for anti-viral drugs and anti-cancer drugs.[2][3] Vidarabine, an antiviral drug, was derived from these compounds.[4] The discovery of these nucleosides also led to the development of cytarabine for clinical use in the treatment of leukemia and lymphoma.[5] Gemcitabine, a fluorinated derivative of cytarabine, is used to treat pancreatic, breast, bladder, and non-small-cell lung cancer.[5] References1. ^1 {{cite WoRMS |title=Tectitethya crypta (de Laubenfels, 1949) |author=van Soest, R. |year=2008 |id=170927 |accessdate=8 April 2017 |db=Porifera}} {{Taxonbar|from=Q3457965}}{{demosponge-stub}}2. ^1 2 {{cite journal |last1=Cerrano |first1=Carlo |last2=Pansini |first2=Maurizio |last3=Valisano|first3=Laura |last4=Calcinai|first4=Barbara |last5=Sarà|first5=Michele |last6=Bavestrello|first6=Giorgio |year=2004 |title= Lagoon sponges from Carrie Bow Cay (Belize): Ecological benefits of selective sediment incorporation |journal=Bollettino dei Musei e degli Istituti Biologici dell'Università di Genova |volume=68 |pages=239–252 | url=https://www.researchgate.net/publication/268401868_LAGOON_SPONGES_FROM_CARRIE_BOW_CAY_BELIZE_ECOLOGICAL_BENEFITS_OF_SELECTIVE_SEDIMENT_INCORPORATION |accessdate=23 June 2012 }} 3. ^1 2 {{cite book|author=Patricia R. Bergquist|title=Sponges|url=https://books.google.com/books?id=MWtPaEo398YC&pg=PA205|accessdate=23 June 2012|year=1978|publisher=University of California Press|isbn=978-0-520-03658-1|page=205}} 4. ^{{cite journal |last1=Sagar |first1=Sunil |last2=Kaur |first2=Mandeep |last3=Minneman |first3=Kenneth P. |title=Antiviral lead compounds from marine sponges |journal=Marine Drugs |date=2010 |volume=8 |issue=10 |pages=2619–2638 |doi=10.3390/md8102619 | pmc=2992996 |pmid=21116410}} 5. ^1 {{cite journal |last1=Schwartsmann |first1=G |last2=Brondani da Rocha |first2=A |last3=Berlinck |first3=RG |last4=Jimeno |first4=J |title=Marine organisms as a source of new anticancer agents |journal=Lancet Oncology |date=April 2001 |volume=2 |issue=4 |pages=221–225 |pmid=11905767 |doi=10.1016/s1470-2045(00)00292-8}} 3 : Hadromerida|Animals described in 1949|Fauna of the Caribbean |
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