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词条 Terpestacin
释义

  1. References

  2. External links

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| InChI = 1/C25H38O4/c1-16-7-6-8-17(2)13-14-25(5)20(11-10-18(3)21(27)12-9-16)22(19(4)15-26)23(28)24(25)29/h7,10,13,19-21,26-28H,6,8-9,11-12,14-15H2,1-5H3/b16-7+,17-13+,18-10+/t19-,20-,21+,25+/m1/s1
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Terpestacin[1] is a fungal metabolite with anticancer activity.

References

1. ^{{cite journal|last1=Chan|first1=Johann|last2=Jamison|first2=Timothy F.|title=Synthesis of (−)-Terpestacin via Catalytic, Stereoselective Fragment Coupling: Siccanol Is Terpestacin, Not 11- -Terpestacin|journal=Journal of the American Chemical Society|date=September 2003|volume=125|issue=38|pages=11514–11515|doi=10.1021/ja0373925|pmid=13129351}}

External links

  • {{cite journal |vauthors=Grigoriev PA, Schlegel B, Schmidtke M, Gräfe U |title=Alteration of membrane polarization by (−)-terpestacin, a biologically active fungal metabolite |journal=Die Pharmazie |volume=57 |issue=9 |pages=653–4|date=September 2002 |pmid=12369460}}
  • {{cite journal |vauthors=Jung HJ, Shim JS, Lee J, Song YM, Park KC, Choi SH, Kim ND, Yoon JH, Mungai PT, Schumacker PT, Kwon HJ |title=Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing|journal=J Biol Chem |volume=285 |issue=15 |pages=11584-95|date=April 2010 |pmid=20145250 |doi=10.1074/jbc.M109.087809 |pmc=2857036}}
  • {{cite journal |vauthors=Park KC, Choi SH |title=Effects of endostatin and a new drug terpestacin against human neuroblastoma xenograft and cell lines |journal=Pediatric Surgery International |volume=29 |issue=12 |pages=1327–40 |date=December 2013 |pmid=24072200 |doi=10.1007/s00383-013-3398-1}}
{{organic-chem-stub}}

1 : Cancer treatments

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