| 词条 | Drug vectorization |
| 释义 |
In pharmacology and medicine vectorization of drugs refers to (intracellular) targeting with plastic, noble metal or silicon nanoparticles or liposomes to which pharmacologically active substances are reversibly bound or attached by adsorption.[1][2] CNRS researchers have devised a way to overcome the problem of multidrug resistance using polyalkylcyanoacrylate (PACA) nanoparticles as "vectors".[3]Drug nanocarriers are expected to play a major role in delivering multiple drugs to tumor tissues by overcoming biological barriers.[4] References1. ^{{cite journal|title=Drug vectorization or how to modulate tissular and cellular distribution of biologically active compounds|author=Couvreur P.|journal=Ann Pharm Fr|year=2001|volume=59|issue=4|pages=232–8|pmid=11468577}} 2. ^{{cite journal|title=Antibody-functionalized porous silicon nanoparticles for vectorization of hydrophobic drugs|journal=Adv Healthc Mater.|year=2013|volume=2|issue=5|pages=718–27|doi=10.1002/adhm.201200335|pmid=23203914}} 3. ^http://www.cnrs.fr/Cnrspresse/en380a6.htm 4. ^{{cite journal|title=Multifunctional nanocarriers for simultaneous encapsulation of hydrophobic and hydrophilic drugs in cancer treatment|journal=Nanomedicine (Lond.)|year=2014|volume=9|issue=10|pages=1499–515|doi=10.2217/nnm.14.97|pmid=25253498}} See also
2 : Pharmacology|Nanomedicine |
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