“Cancer procoagulant”的意思、由来-开放百科全书

词条

Cancer procoagulant

释义

References
External links

{{Infobox enzyme
| Name = Cancer procoagulant
| EC_number = 3.4.22.26
| CAS_number = 109456-80-6
| IUBMB_EC_number = 3/4/22/26
| GO_code =
| image =
| width =
| caption =
}}

Cancer procoagulant is a hypothesised protein, most likely a cysteine protease enzyme ({{EC number|3.4.22.26}}), that occurs only in fetal and malignant cells. Its activity appears to be the activation of factor X, one of the coagulation factors, and would account for the increased incidence of thrombosis in cancer patients. Tissue factor (TF) is also known to be present at increased levels around malignant cells.

References

{{cite journal | vauthors = De Cicco M | title = The prothrombotic state in cancer: pathogenic mechanisms | journal = Critical Reviews in Oncology/hematology | volume = 50 | issue = 3 | pages = 187–96 | date = June 2004 | pmid = 15182825 | doi = 10.1016/j.critrevonc.2003.10.003 | url = }}

External links

{{MeshName|cancer+procoagulant}}

1 : EC 3.4.22

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